| . | IPI . | NCCN-IPI . |
|---|---|---|
| Patient 1 | ||
| Age, 50 y | 0 | 1 |
| Stage IV | 1 | 1 |
| Normalized LDH 1.5 | 1 | 1 |
| ECOG performance status 0 | 0 | 0 |
| Extranodal sites: kidney, bone | 1 | 0 |
| Score | 3 | 3 |
| Risk group | High-intermediate | Low-intermediate |
| 5-y OS estimate | 62% | 82% |
| Patient 2 | ||
| Age, 76 y | 1 | 3 |
| Stage IV | 1 | 1 |
| Normalized LDH 3.5 | 1 | 2 |
| ECOG performance status 1 | 0 | 0 |
| Extranodal sites: bone marrow | 0 | 1 |
| Score | 3 | 7 |
| Risk group | High-intermediate | High |
| 5-y OS estimate | 62% | 33% |
| . | IPI . | NCCN-IPI . |
|---|---|---|
| Patient 1 | ||
| Age, 50 y | 0 | 1 |
| Stage IV | 1 | 1 |
| Normalized LDH 1.5 | 1 | 1 |
| ECOG performance status 0 | 0 | 0 |
| Extranodal sites: kidney, bone | 1 | 0 |
| Score | 3 | 3 |
| Risk group | High-intermediate | Low-intermediate |
| 5-y OS estimate | 62% | 82% |
| Patient 2 | ||
| Age, 76 y | 1 | 3 |
| Stage IV | 1 | 1 |
| Normalized LDH 3.5 | 1 | 2 |
| ECOG performance status 1 | 0 | 0 |
| Extranodal sites: bone marrow | 0 | 1 |
| Score | 3 | 7 |
| Risk group | High-intermediate | High |
| 5-y OS estimate | 62% | 33% |
Illustrative example of how 2 patients with the same prognostic score using the IPI would have very different prognostic scores and survival estimates using the NCCN-IPI.
ECOG, Eastern Cooperative Oncology Group.