Multivariate Cox regression analyses of the NK-AML data set
| Analysis . | OS . | |
|---|---|---|
| Hazard ratio . | P value . | |
| NK-AML patients | ||
| Age | 1.741 | .018 |
| Blast cell count | 1.177 | .264 |
| CEBPA status | 0.786 | .190 |
| Cluster_2 | 2.722 | .004 |
| FLT3 | 2.299 | .002 |
| Sex | 0.962 | .439 |
| NPM1 | 0.432 | .001 |
| CvN method | ||
| Cluster_1 | 0.80 | .276 |
| Custer_2 | 2.51 | .017 |
| Cluster_3 | 0.63 | .144 |
| Cluster_0 | 0.67 | .154 |
| Cluster_4 | 0.64 | .161 |
| Cluster_5 | did not converge | |
| Analysis . | OS . | |
|---|---|---|
| Hazard ratio . | P value . | |
| NK-AML patients | ||
| Age | 1.741 | .018 |
| Blast cell count | 1.177 | .264 |
| CEBPA status | 0.786 | .190 |
| Cluster_2 | 2.722 | .004 |
| FLT3 | 2.299 | .002 |
| Sex | 0.962 | .439 |
| NPM1 | 0.432 | .001 |
| CvN method | ||
| Cluster_1 | 0.80 | .276 |
| Custer_2 | 2.51 | .017 |
| Cluster_3 | 0.63 | .144 |
| Cluster_0 | 0.67 | .154 |
| Cluster_4 | 0.64 | .161 |
| Cluster_5 | did not converge | |
Multivariate Cox regression analyses illustrating the prognostic power of the NK-AML cluster_2. Cluster_2 was analyzed along with other clinical risk factors for the NK-AML patient data set. Cluster_2 was analyzed together with the other clusters identified by the CvN method. Cluster_5 fitting did not converge because of the few events in this cluster. None of the NK-AML clusters identified by the CvC method were significant in the multivariate Cox regression analysis.