Germ-line and somatic hypermutation status of IGHV gene in 50 MBL cases
| MBL subtype . | Mutated N (%) . | Unmutated* N (%) . | Total N (%) . |
|---|---|---|---|
| CLL-like | 25 (80.6) | 6 (19.4) | 31 (100) |
| Atypical | 7 (87.5) | 1 (12.5) | 8 (100) |
| CD5– | 9 (81.8) | 2 (18.2) | 11 (100) |
| Total | 41 (82.0) | 9 (18.0) | 50 (100) |
| MBL subtype . | Mutated N (%) . | Unmutated* N (%) . | Total N (%) . |
|---|---|---|---|
| CLL-like | 25 (80.6) | 6 (19.4) | 31 (100) |
| Atypical | 7 (87.5) | 1 (12.5) | 8 (100) |
| CD5– | 9 (81.8) | 2 (18.2) | 11 (100) |
| Total | 41 (82.0) | 9 (18.0) | 50 (100) |
Having a ≥98% germ-line identity. Includes 5 cases with 100% homology to the corresponding germ-line sequence: 4 CLL-like (2 IGHV3-74, 1 IGHV3-48, and 1 IGHV4-59) and 1 atypical MBL (IGHV3-23).