Table 1 K i and enzyme assay IC 50... | American Society of Hematology

Table 1

K_i and enzyme assay IC₅₀ values of AZD1208

Assay value (nM)	Pim-1	Pim-2	Pim-3
K_i	0.10	1.92	0.40
Enzyme IC₅₀ at K_m [ATP]	0.4	5.0	1.9
Enzyme IC₅₀ at 5 mM [ATP]	2.6	164	17
Cell pBAD IC₅₀	10	151	102

Assay value (nM)	Pim-1	Pim-2	Pim-3
K_i	0.10	1.92	0.40
Enzyme IC₅₀ at K_m [ATP]	0.4	5.0	1.9
Enzyme IC₅₀ at 5 mM [ATP]	2.6	164	17
Cell pBAD IC₅₀	10	151	102

K_m, half-maximal reaction velocity.