Table 1 Cohort characteristics (n = 168)... | American Society of Hematology

Table 1

Cohort characteristics (n = 168)

	N	%
Median age at diagnosis (range), y	56.5 (34-79)
Median follow up (y)	8.3
Median survival (y)	19.8
Median time from diagnosis to blood collection (y)	2.6
Treated during follow-up*	105	63.0
Gender
Male	107	63.7
Female	61	36.3
Rai stage
0	54	42.6
I	43	32.4
II	25	18.4
III-IV	9	6.6
Not determined	37
IGHV/ZAP-70/CD38 status
unmut IGHV/mut IGHV	72/96	42.9/57.1
ZAP-70⁺/ZAP-70⁻	73/95	43.5/56.5
ZAP-70⁻ AND mut IGHV	83	49.4
ZAP-70⁺ AND unmut IGHV	60	35.7
CD38⁺/CD38⁻	49/119	29.2/70.8
Hierarchical cytogenetics (FISH)
del 17p13	12	10.4
del 11q23	12	10.4
del 13q14	47	40.8
Trisomy 12	15	13.0
Normal karyotype	29	25.2
Not determined	53

	N	%
Median age at diagnosis (range), y	56.5 (34-79)
Median follow up (y)	8.3
Median survival (y)	19.8
Median time from diagnosis to blood collection (y)	2.6
Treated during follow-up*	105	63.0
Gender
Male	107	63.7
Female	61	36.3
Rai stage
0	54	42.6
I	43	32.4
II	25	18.4
III-IV	9	6.6
Not determined	37
IGHV/ZAP-70/CD38 status
unmut IGHV/mut IGHV	72/96	42.9/57.1
ZAP-70⁺/ZAP-70⁻	73/95	43.5/56.5
ZAP-70⁻ AND mut IGHV	83	49.4
ZAP-70⁺ AND unmut IGHV	60	35.7
CD38⁺/CD38⁻	49/119	29.2/70.8
Hierarchical cytogenetics (FISH)
del 17p13	12	10.4
del 11q23	12	10.4
del 13q14	47	40.8
Trisomy 12	15	13.0
Normal karyotype	29	25.2
Not determined	53

mut, mutated; unmut, unmutated.

Details provided in supplemental Table 3.