Macroscopic hemorrhagic findings at necropsy on day 56 in a long-term primate model of acquired hemophilia A
| Organ/tissue . | Site . | No. of animals with findings . | ||
|---|---|---|---|---|
| Vehicle, n = 4 . | ACE910, n = 3 . | |||
| Joint | Elbow | Left | 1 | 0 |
| Right | 1 | 0 | ||
| Hip | Left | 4 | 0 | |
| Right | 1 | 0 | ||
| Ankle | Left | 1 | 0 | |
| Skeletal muscle | Lower abdomen | 2 | 0 | |
| Femur | 1 | 0 | ||
| Urinary bladder | Wall | 2 | 0 | |
| Seminal vesicle | Serosa | 1 | 0 | |
| Rectum | Serosa | 1 | 0 | |
| Skin | Back | Subcutis | 1 | 0 |
| Organ/tissue . | Site . | No. of animals with findings . | ||
|---|---|---|---|---|
| Vehicle, n = 4 . | ACE910, n = 3 . | |||
| Joint | Elbow | Left | 1 | 0 |
| Right | 1 | 0 | ||
| Hip | Left | 4 | 0 | |
| Right | 1 | 0 | ||
| Ankle | Left | 1 | 0 | |
| Skeletal muscle | Lower abdomen | 2 | 0 | |
| Femur | 1 | 0 | ||
| Urinary bladder | Wall | 2 | 0 | |
| Seminal vesicle | Serosa | 1 | 0 | |
| Rectum | Serosa | 1 | 0 | |
| Skin | Back | Subcutis | 1 | 0 |