Diagnostic parameters for multiple methods used to evaluate clinical iron overload
| Method . | Normal level . | Mild/moderate iron overload . | Severe iron overload . |
|---|---|---|---|
| Serum ferritin (ng/mL) | <400 | 1000-2500 | >2500 |
| Transferrin saturation (%) | 20-40 | 55-70 in men; 50-70 in women | >70 |
| LIC (mg Fe/g dry weight) | <1.2 | 3-15 | >15 |
| Labile plasma iron (µM) | <0.4 | >0.4 | >0.4 |
| Liver T2* MRI (ms) | >6.3 | <6.3 | <1.4 |
| Cardiac T2* MRI (ms) | >20 | 8-20 | <8 |
| Method . | Normal level . | Mild/moderate iron overload . | Severe iron overload . |
|---|---|---|---|
| Serum ferritin (ng/mL) | <400 | 1000-2500 | >2500 |
| Transferrin saturation (%) | 20-40 | 55-70 in men; 50-70 in women | >70 |
| LIC (mg Fe/g dry weight) | <1.2 | 3-15 | >15 |
| Labile plasma iron (µM) | <0.4 | >0.4 | >0.4 |
| Liver T2* MRI (ms) | >6.3 | <6.3 | <1.4 |
| Cardiac T2* MRI (ms) | >20 | 8-20 | <8 |