Top lenalidomide-regulated putative CRBN-interacting proteins
| . | Experiment 1* . | Experiment 2* . | Experiment 3* . | . | |||
|---|---|---|---|---|---|---|---|
| Proteins . | –Len . | +Len . | –Len . | +Len . | –Len . | +Len . | Regulation . |
| GNL2 | 2 | 0 | 2 | 0 | 2 | 0 | Down |
| STUB1 | 2 | 0 | 2 | 0 | 2 | 0 | Down |
| IKZF1 | 5 | 0 | 6 | 0 | 3 | 0 | Down |
| IKZF3 | 5 | 0 | 7 | 0 | 10 | 0 | Down |
| ANKRD12 | 2 | 1 | 4 | 0 | 6 | 0 | Down |
| KPNA2 | 15 | 2 | 16 | 9 | 36 | 19 | Down |
| CUL4A | 30 | 66 | 34 | 45 | 31 | 58 | Up |
| CUL4B | 18 | 43 | 9 | 45 | 44 | 130 | Up |
| DDB1 | 112 | 179 | 82 | 261 | 122 | 271 | Up |
| SQSTM1 | 11 | 17 | 7 | 17 | 12 | 21 | Up |
| . | Experiment 1* . | Experiment 2* . | Experiment 3* . | . | |||
|---|---|---|---|---|---|---|---|
| Proteins . | –Len . | +Len . | –Len . | +Len . | –Len . | +Len . | Regulation . |
| GNL2 | 2 | 0 | 2 | 0 | 2 | 0 | Down |
| STUB1 | 2 | 0 | 2 | 0 | 2 | 0 | Down |
| IKZF1 | 5 | 0 | 6 | 0 | 3 | 0 | Down |
| IKZF3 | 5 | 0 | 7 | 0 | 10 | 0 | Down |
| ANKRD12 | 2 | 1 | 4 | 0 | 6 | 0 | Down |
| KPNA2 | 15 | 2 | 16 | 9 | 36 | 19 | Down |
| CUL4A | 30 | 66 | 34 | 45 | 31 | 58 | Up |
| CUL4B | 18 | 43 | 9 | 45 | 44 | 130 | Up |
| DDB1 | 112 | 179 | 82 | 261 | 122 | 271 | Up |
| SQSTM1 | 11 | 17 | 7 | 17 | 12 | 21 | Up |
The number in each column represents the number of assigned spectra for that protein.