Table 8

Selected large studies reporting interim PET scan results in patients treated with 6 to 8 cycles of ABVD for advanced-stage Hodgkin lymphoma

No. of patientsOutcome by interim PET scan resultReference
NegativePositive
n (%)FFS, % (y)n (%)FFS, % (y)
260 215 (83) 95 (3) 45 (17) 28 (3) 103, 104 
260 210 (81) 95 (2) 50 (19) 13 (2) 105 
160 137 (86) 92 (2) 23 (14) * 106 
77 61 (79) 96 (2) 16 (21) 0 (2) 107 
91 77 (85) 73 (3) 14 (15) 38 (3) 110 
No. of patientsOutcome by interim PET scan resultReference
NegativePositive
n (%)FFS, % (y)n (%)FFS, % (y)
260 215 (83) 95 (3) 45 (17) 28 (3) 103, 104 
260 210 (81) 95 (2) 50 (19) 13 (2) 105 
160 137 (86) 92 (2) 23 (14) * 106 
77 61 (79) 96 (2) 16 (21) 0 (2) 107 
91 77 (85) 73 (3) 14 (15) 38 (3) 110 

Interim PET scans were performed after 2 cycles of chemotherapy.

*

Positive interim PET scan outcome is not interpretable due to change in chemotherapy.

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