Table 1

Baseline characteristics of the patients

EnoxaparinPlacebo
138 118 
Age, y (mean (SD)) 32.7 ± 5.2 32.1 ± 5.4 
 >35 y, n (%) 44 (31.9) 42 (35.6) 
Body mass index, kg/m2 (mean ± SD) 23.9 ± 4.4 23.9 ± 5 
Daily smoking ≥1 cigarette, n (%) 22 (15.9) 26 (22) 
Systolic blood pressure*, mm Hg (mean [SD]) 118 (11) 118 (12) 
Diastolic blood pressure*, mm Hg (mean [SD]) 69 (9) 67 (9) 
Previous venous thromboembolic event, n (%) 0 (0) 2 (1.7) 
Gestation at inclusion, days (mean ± SD) 39.1 ± 10.3 38.9 ± 9.3 
Previous live birth, n (%) 66 (47.8) 50 (42.3) 
Number of previous miscarriage, n (median [range]) 3 (2-7) 3 (2-9) 
 ≥3 miscarriages, n (%) 100 (72.5) 86 (72.9) 
 One or more loss ≥10 wk, n (%) 47 (34) 39 (33) 
Randomization strata, n (%)   
 1 51 (37) 45 (38.1) 
 2 65 (47.1) 54 (45.8) 
 3 22 (15.9) 19 (16.1) 
EnoxaparinPlacebo
138 118 
Age, y (mean (SD)) 32.7 ± 5.2 32.1 ± 5.4 
 >35 y, n (%) 44 (31.9) 42 (35.6) 
Body mass index, kg/m2 (mean ± SD) 23.9 ± 4.4 23.9 ± 5 
Daily smoking ≥1 cigarette, n (%) 22 (15.9) 26 (22) 
Systolic blood pressure*, mm Hg (mean [SD]) 118 (11) 118 (12) 
Diastolic blood pressure*, mm Hg (mean [SD]) 69 (9) 67 (9) 
Previous venous thromboembolic event, n (%) 0 (0) 2 (1.7) 
Gestation at inclusion, days (mean ± SD) 39.1 ± 10.3 38.9 ± 9.3 
Previous live birth, n (%) 66 (47.8) 50 (42.3) 
Number of previous miscarriage, n (median [range]) 3 (2-7) 3 (2-9) 
 ≥3 miscarriages, n (%) 100 (72.5) 86 (72.9) 
 One or more loss ≥10 wk, n (%) 47 (34) 39 (33) 
Randomization strata, n (%)   
 1 51 (37) 45 (38.1) 
 2 65 (47.1) 54 (45.8) 
 3 22 (15.9) 19 (16.1) 
*

At inclusion.

Two missing data in each intervention group.

Strata 1: (2 previous miscarriages and age <35 y) or (3 previous miscarriages and age <30 y) or (4 or 5 previous miscarriages and age <25 y). Strata 2: (2 previous miscarriages and 35 ≤ age <40 y) or (3 previous miscarriages and 30 ≤ age <40 y) or (4 or 5 previous miscarriages and 25 ≤age <35 y). Strata 3: (2 or 3 previous miscarriages and age ≥40 y) or (4 or 5 previous miscarriages and age ≥35 y).

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