Baseline characteristics of the patients
. | Enoxaparin . | Placebo . |
---|---|---|
N | 138 | 118 |
Age, y (mean (SD)) | 32.7 ± 5.2 | 32.1 ± 5.4 |
>35 y, n (%) | 44 (31.9) | 42 (35.6) |
Body mass index, kg/m2 (mean ± SD) | 23.9 ± 4.4 | 23.9 ± 5 |
Daily smoking ≥1 cigarette, n (%) | 22 (15.9) | 26 (22) |
Systolic blood pressure*, mm Hg (mean [SD]) | 118 (11) | 118 (12) |
Diastolic blood pressure*, mm Hg (mean [SD]) | 69 (9) | 67 (9) |
Previous venous thromboembolic event, n (%) | 0 (0) | 2 (1.7) |
Gestation at inclusion, days (mean ± SD) | 39.1 ± 10.3 | 38.9 ± 9.3 |
Previous live birth, n (%) | 66 (47.8) | 50 (42.3) |
Number of previous miscarriage, n (median [range]) | 3 (2-7) | 3 (2-9) |
≥3 miscarriages, n (%) | 100 (72.5) | 86 (72.9) |
One or more loss ≥10 wk†, n (%) | 47 (34) | 39 (33) |
Randomization strata, n (%)‡ | ||
1 | 51 (37) | 45 (38.1) |
2 | 65 (47.1) | 54 (45.8) |
3 | 22 (15.9) | 19 (16.1) |
. | Enoxaparin . | Placebo . |
---|---|---|
N | 138 | 118 |
Age, y (mean (SD)) | 32.7 ± 5.2 | 32.1 ± 5.4 |
>35 y, n (%) | 44 (31.9) | 42 (35.6) |
Body mass index, kg/m2 (mean ± SD) | 23.9 ± 4.4 | 23.9 ± 5 |
Daily smoking ≥1 cigarette, n (%) | 22 (15.9) | 26 (22) |
Systolic blood pressure*, mm Hg (mean [SD]) | 118 (11) | 118 (12) |
Diastolic blood pressure*, mm Hg (mean [SD]) | 69 (9) | 67 (9) |
Previous venous thromboembolic event, n (%) | 0 (0) | 2 (1.7) |
Gestation at inclusion, days (mean ± SD) | 39.1 ± 10.3 | 38.9 ± 9.3 |
Previous live birth, n (%) | 66 (47.8) | 50 (42.3) |
Number of previous miscarriage, n (median [range]) | 3 (2-7) | 3 (2-9) |
≥3 miscarriages, n (%) | 100 (72.5) | 86 (72.9) |
One or more loss ≥10 wk†, n (%) | 47 (34) | 39 (33) |
Randomization strata, n (%)‡ | ||
1 | 51 (37) | 45 (38.1) |
2 | 65 (47.1) | 54 (45.8) |
3 | 22 (15.9) | 19 (16.1) |
At inclusion.
Two missing data in each intervention group.
Strata 1: (2 previous miscarriages and age <35 y) or (3 previous miscarriages and age <30 y) or (4 or 5 previous miscarriages and age <25 y). Strata 2: (2 previous miscarriages and 35 ≤ age <40 y) or (3 previous miscarriages and 30 ≤ age <40 y) or (4 or 5 previous miscarriages and 25 ≤age <35 y). Strata 3: (2 or 3 previous miscarriages and age ≥40 y) or (4 or 5 previous miscarriages and age ≥35 y).