Table 2 Linear mixed model analysis for... | American Society of Hematology

Table 2

Linear mixed model analysis for longitudinal endpoints

Endpoint, predictor, and cutoff	β	95% CI	P
Neurodevelopment (DQ/IQ)
Sex
Male	1
Female	6.55	0.24-12.86	.04
Baseline DQ/IQ
<85*	1
≥85*	8.58	2.21-14.95	.009
Age at HCT
<16 months†	1
≥16 months†	−8.40	−14.62 to −2.19	.009
TBI
No	1
Yes	−9.90	−18.82 to −0.98	.03
Follow-up age, months	−0.09	−0.13 to −0.05	<.001
Height (SD)
Baseline height (SD)	0.49	0.39-0.60	<.001
IDUA level
<Reference‡	1
≥Reference‡	0.43	0.08-0.77	.02
TBI
No	1
Yes	−1.01	−1.53 to −0.48	<.001
Follow-up age, months	−0.02	−0.02 to −0.02	<.001

Endpoint, predictor, and cutoff	β	95% CI	P
Neurodevelopment (DQ/IQ)
Sex
Male	1
Female	6.55	0.24-12.86	.04
Baseline DQ/IQ
<85*	1
≥85*	8.58	2.21-14.95	.009
Age at HCT
<16 months†	1
≥16 months†	−8.40	−14.62 to −2.19	.009
TBI
No	1
Yes	−9.90	−18.82 to −0.98	.03
Follow-up age, months	−0.09	−0.13 to −0.05	<.001
Height (SD)
Baseline height (SD)	0.49	0.39-0.60	<.001
IDUA level
<Reference‡	1
≥Reference‡	0.43	0.08-0.77	.02
TBI
No	1
Yes	−1.01	−1.53 to −0.48	<.001
Follow-up age, months	−0.02	−0.02 to −0.02	<.001

Only statistically significant results are shown. β indicates estimate.

Median baseline DQ/IQ.

Median age at HCT.

Lower limit of local reference.