Table 2

Multivariate analysis of prognostic factors for OS in AML

VariableTotal populationCensored for allograft
HR95% CIPHR95% CIP
High INPP4B 2.2 1.27-3.67 <.01 2.0 1.1-3.66 .02 
Adverse karyotype 1.74 1.07-2.81 .03 1.55 0.87-2.74 .14 
Age >55 y 2.13 1.43-3.18 <.01 6.3 3.48-11.57 <.01 
WBC >100 × 109/L 1.7 0.92-3.19 .09 1.62 0.73-3.6 .24 
Secondary AML 1.65 0.89-3.06 .11 1.91 0.85-4.26 .12 
VariableTotal populationCensored for allograft
HR95% CIPHR95% CIP
High INPP4B 2.2 1.27-3.67 <.01 2.0 1.1-3.66 .02 
Adverse karyotype 1.74 1.07-2.81 .03 1.55 0.87-2.74 .14 
Age >55 y 2.13 1.43-3.18 <.01 6.3 3.48-11.57 <.01 
WBC >100 × 109/L 1.7 0.92-3.19 .09 1.62 0.73-3.6 .24 
Secondary AML 1.65 0.89-3.06 .11 1.91 0.85-4.26 .12 

CI, confidence interval.

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