Levels of evidence for drugs reported to cause TMA
Levels of evidence . | Individual patient reports . | Patient group reports . | No. of drugs . |
---|---|---|---|
Definite | 104 | 0 | 22 |
Probable | 55 | 5 | 20 additional drugs |
Possible | 363 | 40 | 27 additional drugs |
Unlikely | 64 | 1 | 9 additional drugs |
Total | 586 | 46 | 78 |
Levels of evidence . | Individual patient reports . | Patient group reports . | No. of drugs . |
---|---|---|---|
Definite | 104 | 0 | 22 |
Probable | 55 | 5 | 20 additional drugs |
Possible | 363 | 40 | 27 additional drugs |
Unlikely | 64 | 1 | 9 additional drugs |
Total | 586 | 46 | 78 |
The 586 individual patients were reported in 344 articles. The 46 patient groups were reported in 43 articles. These 387 articles reported 78 drugs. In the column describing the number of drugs, each drug is listed only once according to its highest level of evidence. The analysis of all 387 articles is described, with their citation, in supplemental Table 3.