Table 1

Clinical features, and signs and symptoms of TTP

Clinical featureSigns/symptoms
MAHA Pallor, weakness, fatigue, jaundice 
Thrombocytopenia Petechiae and occasionally purpura 
Bowel ischemia Abdominal pain, nausea, vomiting, diarrhea 
Cardiac ischemia Chest pain, hypotension, heart failure 
Central nervous system ischemia Common: confusion, headache 
Less common: coma, encephalopathy, stroke, seizure, focal abnormalities 
Renal ischemia Hematuria, proteinuria 
Fever Fever (high fever with chills suspect other diagnosis) 
Clinical featureSigns/symptoms
MAHA Pallor, weakness, fatigue, jaundice 
Thrombocytopenia Petechiae and occasionally purpura 
Bowel ischemia Abdominal pain, nausea, vomiting, diarrhea 
Cardiac ischemia Chest pain, hypotension, heart failure 
Central nervous system ischemia Common: confusion, headache 
Less common: coma, encephalopathy, stroke, seizure, focal abnormalities 
Renal ischemia Hematuria, proteinuria 
Fever Fever (high fever with chills suspect other diagnosis) 

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