Laboratory findings suggestive of acquired TTP
| Laboratory data . | Results . |
|---|---|
| Platelet count, ×103/μL | <30 |
| Hemoglobin, g/dL | <10 |
| Lactate dehydrogenase | Elevated |
| Haptoglobin | Decreased |
| Reticulocyte count | Increased |
| Indirect bilirubin | Increased |
| Peripheral blood smear | Increased schistocytes, nucleated red blood cells* |
| Creatinine | Mildly increased (<1.5 mg/dL) |
| Troponin T | May be increased |
| INR, PTT, fibrinogen | Normal |
| Laboratory data . | Results . |
|---|---|
| Platelet count, ×103/μL | <30 |
| Hemoglobin, g/dL | <10 |
| Lactate dehydrogenase | Elevated |
| Haptoglobin | Decreased |
| Reticulocyte count | Increased |
| Indirect bilirubin | Increased |
| Peripheral blood smear | Increased schistocytes, nucleated red blood cells* |
| Creatinine | Mildly increased (<1.5 mg/dL) |
| Troponin T | May be increased |
| INR, PTT, fibrinogen | Normal |
INR, international normalized ratio; PTT, partial thromboplastin time.
Consider a bone marrow biopsy in the presence of numerous nucleated red blood cells to rule out an alternative etiology, for example, occult systemic malignancy.9-12