Table 3

Binding studies of [3H]PSB-0413 on intact platelets from the propositus (III-7) and his brother (III-1) and 10 healthy controls

Patient III-7, experiment 1Patient III-7, experiment 2Patient III-1Healthy controls* (n = 10)
Bmax (sites per platelet) 285 436 693 425 ± 50 
KD (nM) 8.4 33.0 19.0 3.3 ± 0.6 
Patient III-7, experiment 1Patient III-7, experiment 2Patient III-1Healthy controls* (n = 10)
Bmax (sites per platelet) 285 436 693 425 ± 50 
KD (nM) 8.4 33.0 19.0 3.3 ± 0.6 
*

Means ± SD.

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