Table 1 Conditioning regimens and stem... | American Society of Hematology

Table 1

Conditioning regimens and stem cell source by trial

	Trial 1	Trial 2	Trial 3	Trial 4
No. patients	23	43	16	48
Time period	1995-1998	1999-2003	2004-2006	2006-2012
Conditioning regimen	TBI 450-600, CY,* ATG†	TBI 450, FLU,‡ CY,* ATG†	TBI 450 + TS, FLU,‡ CY,* ATG†	TBI 300§ + TS, FLU,‡ CY,* ATG†
Stem cell source
1-Ag MM-related TCD BM	2	2	0	4
HLA-matched URD TCD BM	10	31	8	24
1-Ag MM URD TCD BM	8	5	1	4
6/6 URD UCB	1	2	1	3
4-5/6 URD UCB	2	3	5	11
6/6 + 5/6 double URD UCB	0	0	1	0
5/6 + 5/6 double URD UCB	0	0	0	2
Follow-up (median, range, y)	18 (17-18)	12 (10-14)	9 (7-10)	4 (2-8)

	Trial 1	Trial 2	Trial 3	Trial 4
No. patients	23	43	16	48
Time period	1995-1998	1999-2003	2004-2006	2006-2012
Conditioning regimen	TBI 450-600, CY,* ATG†	TBI 450, FLU,‡ CY,* ATG†	TBI 450 + TS, FLU,‡ CY,* ATG†	TBI 300§ + TS, FLU,‡ CY,* ATG†
Stem cell source
1-Ag MM-related TCD BM	2	2	0	4
HLA-matched URD TCD BM	10	31	8	24
1-Ag MM URD TCD BM	8	5	1	4
6/6 URD UCB	1	2	1	3
4-5/6 URD UCB	2	3	5	11
6/6 + 5/6 double URD UCB	0	0	1	0
5/6 + 5/6 double URD UCB	0	0	0	2
Follow-up (median, range, y)	18 (17-18)	12 (10-14)	9 (7-10)	4 (2-8)

Ag, antigen; MM, mismatched; TCD, T-cell depleted; TS, thymic shielding; URD, unrelated donor.

10 mg/kg per day × 4 d.

30 mg/kg per day × 5 d.

35 mg/m² per day × 4 d.

2 patients received TBI 150.