Characteristics of the groups of patients with SS, patients in use of HU, and CG
| . | SS (n) . | SS-HU (n) . | CG (n) . |
|---|---|---|---|
| Age (y) | 30.5 (21.2-46.2) | 29.5 (24-37) | 31 (27-39.2) |
| (20) | (20) | (22) | |
| Gender (M/F) | 8/12 | 4/16 | 9/13 |
| Hemoglobin (g/dL) | 9.2 (7.9-10) | 9.5 (8.4-10.1) | 14.1 (13.7-15.2)* |
| (20) | (20) | (19) | |
| Mean corpuscular volume (fL) | 86.8 (78.2-96) | 111 (106-116.3)† | 90.1 (86.2-92.1) |
| (20) | (20) | (19) | |
| Lactate dehydrogenase (U/L) | 526 (384-691) | 351.5 (280.5-425.5) | 152 (136-172)* |
| (20) | (20) | (19) | |
| LDH-1 (U/L) | 225.7 (161.6-318.1) | 154.9 (115.7-180.8) | 31 (27.5-37.2)* |
| (20) | (19) | (16) | |
| LDH-2 (U/L) | 203.2 (146-268.7) | 132.5 (102-159.8) | 60.5 (52.9-70.2)* |
| (20) | (19) | (16) | |
| LDH-3 (U/L) | 56 (38.2-70.1)‡ | 33.7 (31.7-40.8) | 28.5 (25.3-34.3) |
| (20) | (19) | (16) | |
| LDH-4 (U/L) | 20.3 (14.9-24.9) | 17.5 (14.2-18.7) | 17.3 (12.7-20.5) |
| (20) | (19) | (16) | |
| LDH-5 (U/L) | 15.1 (11.7-19.8) | 12.9 (11.3-17.1) | 16.5 (14.3-23.9) |
| (20) | (19) | (16) | |
| Plasma hemoglobin (µg/dcL) | 104.6 (44.5-223.8) | 51.2 (30.1-77.6) | 14.4 (10.3-30.4)* |
| (20) | (20) | (22) | |
| Haptoglobin (µg/dL) | 0.1 (0.0-0.3) | 0.6 (0.1-1.6) | 116.7 (75.9-151.2)* |
| (20) | (20) | (21) | |
| Microvesicles (µL) | 32 185 (17 059-53 980) | 21 643 (9942-41 673) | 5595 (3886-8691)* |
| (20) | (20) | (20) |
| . | SS (n) . | SS-HU (n) . | CG (n) . |
|---|---|---|---|
| Age (y) | 30.5 (21.2-46.2) | 29.5 (24-37) | 31 (27-39.2) |
| (20) | (20) | (22) | |
| Gender (M/F) | 8/12 | 4/16 | 9/13 |
| Hemoglobin (g/dL) | 9.2 (7.9-10) | 9.5 (8.4-10.1) | 14.1 (13.7-15.2)* |
| (20) | (20) | (19) | |
| Mean corpuscular volume (fL) | 86.8 (78.2-96) | 111 (106-116.3)† | 90.1 (86.2-92.1) |
| (20) | (20) | (19) | |
| Lactate dehydrogenase (U/L) | 526 (384-691) | 351.5 (280.5-425.5) | 152 (136-172)* |
| (20) | (20) | (19) | |
| LDH-1 (U/L) | 225.7 (161.6-318.1) | 154.9 (115.7-180.8) | 31 (27.5-37.2)* |
| (20) | (19) | (16) | |
| LDH-2 (U/L) | 203.2 (146-268.7) | 132.5 (102-159.8) | 60.5 (52.9-70.2)* |
| (20) | (19) | (16) | |
| LDH-3 (U/L) | 56 (38.2-70.1)‡ | 33.7 (31.7-40.8) | 28.5 (25.3-34.3) |
| (20) | (19) | (16) | |
| LDH-4 (U/L) | 20.3 (14.9-24.9) | 17.5 (14.2-18.7) | 17.3 (12.7-20.5) |
| (20) | (19) | (16) | |
| LDH-5 (U/L) | 15.1 (11.7-19.8) | 12.9 (11.3-17.1) | 16.5 (14.3-23.9) |
| (20) | (19) | (16) | |
| Plasma hemoglobin (µg/dcL) | 104.6 (44.5-223.8) | 51.2 (30.1-77.6) | 14.4 (10.3-30.4)* |
| (20) | (20) | (22) | |
| Haptoglobin (µg/dL) | 0.1 (0.0-0.3) | 0.6 (0.1-1.6) | 116.7 (75.9-151.2)* |
| (20) | (20) | (21) | |
| Microvesicles (µL) | 32 185 (17 059-53 980) | 21 643 (9942-41 673) | 5595 (3886-8691)* |
| (20) | (20) | (20) |