Table 1

Bone-related genes are regulated by Runx2 in MM cells

ClassesGene symbolGene nameFold change
Runx2 k/dRunx2 k/in
Osteoblast BGLAP Osteocalcin (OCN) −3.25 1.22 
SPP1 Osteopontin (OPN) −2.09 4.32 
Osteoclast CTSK Cathepsin K −15.12 2.73 
RANK Receptor activator of nuclear factor κB −7.45 2.27 
MMP9 Matrix metallopeptidase 9 −8.93 4.12 
Osteocyte DMP1 Dentin matrix protein 1 −2.02 7.36 
Adhesion molecule CD44 CD44 −6.64 1.26 
ITGA4 Integrin α4 −5.23 1.26 
ClassesGene symbolGene nameFold change
Runx2 k/dRunx2 k/in
Osteoblast BGLAP Osteocalcin (OCN) −3.25 1.22 
SPP1 Osteopontin (OPN) −2.09 4.32 
Osteoclast CTSK Cathepsin K −15.12 2.73 
RANK Receptor activator of nuclear factor κB −7.45 2.27 
MMP9 Matrix metallopeptidase 9 −8.93 4.12 
Osteocyte DMP1 Dentin matrix protein 1 −2.02 7.36 
Adhesion molecule CD44 CD44 −6.64 1.26 
ITGA4 Integrin α4 −5.23 1.26 
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