Table 4

Treatment-emergent AEs occurring in ≥25% of patients with B-cell lymphomas treated with single-agent brentuximab vedotin

AEDLBCL (n = 49)Other B-cell lymphomas (n = 19)
Grade 1/2Grade 3/4*TotalGrade 1/2Grade 3/4Total
No.%No.%No.%No.%No.%No.%
Fatigue 21 43 12 27 55 26  26 
Diarrhea 18 37 21 43 21 26 
Neutropenia 18 37 20 41 26 32 
Nausea 13 27 12 19 39 21 26 
Decreased appetite 11 22 15 31    
Pyrexia 13 27 15 31 26  26 
Peripheral sensory neuropathy 12 24 14 29 21  21 
AEDLBCL (n = 49)Other B-cell lymphomas (n = 19)
Grade 1/2Grade 3/4*TotalGrade 1/2Grade 3/4Total
No.%No.%No.%No.%No.%No.%
Fatigue 21 43 12 27 55 26  26 
Diarrhea 18 37 21 43 21 26 
Neutropenia 18 37 20 41 26 32 
Nausea 13 27 12 19 39 21 26 
Decreased appetite 11 22 15 31    
Pyrexia 13 27 15 31 26  26 
Peripheral sensory neuropathy 12 24 14 29 21  21 
*

All AEs were grade 3 with the exception of grade 4 neutropenia in 9 patients (18%).

All AEs were grade 3 with the exception of grade 4 neutropenia in 2 patients (11%).

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