Characteristics of adult African-American participants in the CSSCD with SCA who completed PFT compared with those who did not
| . | Adult SCA participants with PFT (n = 430) . | Adult SCA participants without PFT (n = 865)* . | P value . |
|---|---|---|---|
| Demographic and clinical characteristics | |||
| Age at study entry (y) | 27.4 ± 7.4† | 22.6 ± 9.8 | <.001 |
| Age at end of study (y) | 36.0 ± 7.4 | 30.7 ± 9.3 | <.001 |
| Males (%) | 41.2 | 45.2 | .168 |
| ACS rate (events/patient-y), total duration of study | 0.07 ± 0.14 | 0.07 ± 0.29 | .104‡ |
| Pain rate (events/patient-y), total duration of study | 0.98 ± 1.88 | 1.05 ± 2.07 | .424‡ |
| Asthma diagnosis (%) (n = 374) | 4.5 | 4.5 | 1.00 |
| History of chronic transfusion (%) | 12.6 | 11.7 | .645 |
| Laboratory characteristics | |||
| White blood cell count (109/L) (n = 426) | 11.6 ± 2.5 | 12.0 ± 2.8 | .027 |
| Fetal hemoglobin (g/dL) (n = 416) | 5.7 ± 4.1 | 6.1 ± 4.1 | .123 |
| Hemoglobin (g/dL) (n = 427) | 8.6 ± 1.2 | 8.5 ± 1.3 | .258 |
| Platelet count (109/L) (n = 422) | 419.9 ± 114.5 | 440.8 ± 126.6 | .004 |
| Hematocrit (%) (n = 428) | 25.3 ± 3.7 | 24.9 ± 4.0 | .100 |
| History of renal insufficiency (%) | 3.7 | 3.9 | .854 |
| Bilirubin (mg/dL) (n = 427) | 3.3 ± 2.0 | 3.6 ± 2.0 | .025 |
| Lactic dehydrogenase (mg/dL) (n = 417) | 477.4 ± 174.0 | 496.5 ± 202.1 | .101 |
| . | Adult SCA participants with PFT (n = 430) . | Adult SCA participants without PFT (n = 865)* . | P value . |
|---|---|---|---|
| Demographic and clinical characteristics | |||
| Age at study entry (y) | 27.4 ± 7.4† | 22.6 ± 9.8 | <.001 |
| Age at end of study (y) | 36.0 ± 7.4 | 30.7 ± 9.3 | <.001 |
| Males (%) | 41.2 | 45.2 | .168 |
| ACS rate (events/patient-y), total duration of study | 0.07 ± 0.14 | 0.07 ± 0.29 | .104‡ |
| Pain rate (events/patient-y), total duration of study | 0.98 ± 1.88 | 1.05 ± 2.07 | .424‡ |
| Asthma diagnosis (%) (n = 374) | 4.5 | 4.5 | 1.00 |
| History of chronic transfusion (%) | 12.6 | 11.7 | .645 |
| Laboratory characteristics | |||
| White blood cell count (109/L) (n = 426) | 11.6 ± 2.5 | 12.0 ± 2.8 | .027 |
| Fetal hemoglobin (g/dL) (n = 416) | 5.7 ± 4.1 | 6.1 ± 4.1 | .123 |
| Hemoglobin (g/dL) (n = 427) | 8.6 ± 1.2 | 8.5 ± 1.3 | .258 |
| Platelet count (109/L) (n = 422) | 419.9 ± 114.5 | 440.8 ± 126.6 | .004 |
| Hematocrit (%) (n = 428) | 25.3 ± 3.7 | 24.9 ± 4.0 | .100 |
| History of renal insufficiency (%) | 3.7 | 3.9 | .854 |
| Bilirubin (mg/dL) (n = 427) | 3.3 ± 2.0 | 3.6 ± 2.0 | .025 |
| Lactic dehydrogenase (mg/dL) (n = 417) | 477.4 ± 174.0 | 496.5 ± 202.1 | .101 |