Estimated incidence of a first episode of venous thrombosis in carriers over the age of 15 of various thrombophilic disorders
| . | AT, PC, or PS deficiency . | FVL mutation . | PTM . |
|---|---|---|---|
| Overall (%/year) | 1.5 (0.7-2.8) | 0.5 (0.1-1.3) | 0.4 (0.1-1.1) |
| Surgery, trauma, or immobilization (%/episode) | 8.1 (4.5-13.2) | 1.8 (0.7-4.0) | 1.6 (0.5-3.8) |
| Pregnancy (%/pregnancy) | 4.1 (1.7-8.3) | 2.1 (0.7-4.9) | 2.3 (0.8-5.3) |
| During pregnancy (%) | 1.2 (0.3-4.2) | 0.4 (0.1-2.4) | 0.5 (0.1-2.6) |
| Postpartum period (%) | 3.0 (1.3-6.7) | 1.7 (0.7-4.3) | 1.9 (0.7-4.7) |
| Oral contraceptive use (%/year of use) | 4.3 (1.4-9.7) | 0.5 (0.1-1.4) | 0.2 (0.0-0.9) |
| . | AT, PC, or PS deficiency . | FVL mutation . | PTM . |
|---|---|---|---|
| Overall (%/year) | 1.5 (0.7-2.8) | 0.5 (0.1-1.3) | 0.4 (0.1-1.1) |
| Surgery, trauma, or immobilization (%/episode) | 8.1 (4.5-13.2) | 1.8 (0.7-4.0) | 1.6 (0.5-3.8) |
| Pregnancy (%/pregnancy) | 4.1 (1.7-8.3) | 2.1 (0.7-4.9) | 2.3 (0.8-5.3) |
| During pregnancy (%) | 1.2 (0.3-4.2) | 0.4 (0.1-2.4) | 0.5 (0.1-2.6) |
| Postpartum period (%) | 3.0 (1.3-6.7) | 1.7 (0.7-4.3) | 1.9 (0.7-4.7) |
| Oral contraceptive use (%/year of use) | 4.3 (1.4-9.7) | 0.5 (0.1-1.4) | 0.2 (0.0-0.9) |
Values are percentages (95% CI). Data apply to individuals with at least 1 symptomatic first-degree relative.37