Basic blood parameters of Vps33bfl/fl-ERT2 mice
| Hematological parameters . | Vps33bfl/fl (Mean ± SEM; n = 35) . | Vps33bfl/fl-ERT2 (Mean ± SEM; n = 26) . |
|---|---|---|
| PLT (×103/μL) | 893.5 ± 160.6 | 1136.0 ± 160.4*** |
| MPV (fL) | 5.5 ± 0.4 | 5.9 ± 0.5** |
| WBC (×103/μL) | 4.1 ± 0.3 | 5.2 ± 0.4 |
| RBC (×106/μL) | 6.2 ± 0.3 | 5.9 ± 0.1 |
| HCT (%) | 29.4 ± 0.6 | 28.1 ± 0.7 |
| LYM (%) | 80.7 ± 1.6 | 70.9 ± 2.3*** |
| MON (%) | 7.3 ± 0.9 | 16.0 ± 2.0*** |
| NEU (%) | 8.0 ± 0.5 | 11.0 ± 0.9** |
| EOS (%) | 0.7 ± 0.2 | 0.9 ± 0.3 |
| BAS (%) | 0.7 ± 0.2 | 1.1 ± 0.4 |
| Hematological parameters . | Vps33bfl/fl (Mean ± SEM; n = 35) . | Vps33bfl/fl-ERT2 (Mean ± SEM; n = 26) . |
|---|---|---|
| PLT (×103/μL) | 893.5 ± 160.6 | 1136.0 ± 160.4*** |
| MPV (fL) | 5.5 ± 0.4 | 5.9 ± 0.5** |
| WBC (×103/μL) | 4.1 ± 0.3 | 5.2 ± 0.4 |
| RBC (×106/μL) | 6.2 ± 0.3 | 5.9 ± 0.1 |
| HCT (%) | 29.4 ± 0.6 | 28.1 ± 0.7 |
| LYM (%) | 80.7 ± 1.6 | 70.9 ± 2.3*** |
| MON (%) | 7.3 ± 0.9 | 16.0 ± 2.0*** |
| NEU (%) | 8.0 ± 0.5 | 11.0 ± 0.9** |
| EOS (%) | 0.7 ± 0.2 | 0.9 ± 0.3 |
| BAS (%) | 0.7 ± 0.2 | 1.1 ± 0.4 |
Diluted whole blood was analyzed using an ABX Pentra 60 hematology analyzer.
BAS, basophils; EOS, eosinophils; HCT, hematocrit; LYM, lymphocytes; MON, monocytes; MPV, mean platelet volume; NEU, neutrophils; PLT, platelets; RBC, red blood cells; WBC, white blood cells.
**P < .01; ***P < .001.