Treatment-emergent AEs occurring in at least 15% of patients treated with frontline brentuximab vedotin monotherapy
. | N = 27 . | ||
---|---|---|---|
Event* . | Grade 1/2 n (%) . | Grade 3† n (%) . | Total n (%) . |
Peripheral sensory neuropathy | 14 (52) | 7 (26) | 21 (78) |
Fatigue | 12 (44) | 0 | 12 (44) |
Nausea | 12 (44) | 0 | 12 (44) |
Peripheral edema | 10 (37) | 0 | 10 (37) |
Diarrhea | 9 (33) | 0 | 9 (33) |
Decreased appetite | 8 (30) | 0 | 8 (30) |
Constipation | 7 (26) | 0 | 7 (26) |
Alopecia | 5 (19) | 0 | 5 (19) |
Cough | 5 (19) | 0 | 5 (19) |
Muscular weakness | 5 (19) | 0 | 5 (19) |
Pruritus | 5 (19) | 0 | 5 (19) |
Rash | 3 (11) | 2 (7) | 5 (19) |
Urinary tract infection | 4 (15) | 1 (4) | 5 (19) |
Vomiting | 5 (19) | 0 | 5 (19) |
Deep vein thrombosis | 4 (15) | 0 | 4 (15) |
Dizziness | 4 (15) | 0 | 4 (15) |
Maculopapular rash | 3 (11) | 1 (4) | 4 (15) |
Weight decreased | 4 (15) | 0 | 4 (15) |
. | N = 27 . | ||
---|---|---|---|
Event* . | Grade 1/2 n (%) . | Grade 3† n (%) . | Total n (%) . |
Peripheral sensory neuropathy | 14 (52) | 7 (26) | 21 (78) |
Fatigue | 12 (44) | 0 | 12 (44) |
Nausea | 12 (44) | 0 | 12 (44) |
Peripheral edema | 10 (37) | 0 | 10 (37) |
Diarrhea | 9 (33) | 0 | 9 (33) |
Decreased appetite | 8 (30) | 0 | 8 (30) |
Constipation | 7 (26) | 0 | 7 (26) |
Alopecia | 5 (19) | 0 | 5 (19) |
Cough | 5 (19) | 0 | 5 (19) |
Muscular weakness | 5 (19) | 0 | 5 (19) |
Pruritus | 5 (19) | 0 | 5 (19) |
Rash | 3 (11) | 2 (7) | 5 (19) |
Urinary tract infection | 4 (15) | 1 (4) | 5 (19) |
Vomiting | 5 (19) | 0 | 5 (19) |
Deep vein thrombosis | 4 (15) | 0 | 4 (15) |
Dizziness | 4 (15) | 0 | 4 (15) |
Maculopapular rash | 3 (11) | 1 (4) | 4 (15) |
Weight decreased | 4 (15) | 0 | 4 (15) |