Indications for irradiation of blood components for prevention of TA-GVHD
| Indication . | Institution . | ||
|---|---|---|---|
| MGH . | SBK/UHN . | HSC . | |
| Stem cell transplant recipients | ✔ | ✔ | ✔ |
| Congenital immunodeficiencies or infants with features suggestive of an undiagnosed immunodeficiency | ✔ | ✔ | ✔ |
| Intrauterine transfusion | ✔ | ✔ | ✔ |
| Premature, low birth weight | ✔ | ✔ | ✔ |
| Term infants (<6 months old old) | ✔ | ✔ | |
| Acute lymphoplastic leukemia | ✔ | ✔ | ✔ |
| Other lymphoid malignancies | ✔ | ✔ | ✔ |
| Acute myeloid leukemia | ✔ | ✔ | |
| Chronic leukemias | ✔ | ✔ | |
| Stem cell donors during harvest | ✔ | ||
| Fludarabine, alemtuzumab, and ATG recipients | ✔ | ✔ | ✔ |
| Children on intensive myeloablative chemotherapy regimens | ✔ | ✔ | |
| Children with solid tumors or malignant hematologic disease | ✔ | ||
| Children with solid organ transplants | ✔ | ||
| Indication . | Institution . | ||
|---|---|---|---|
| MGH . | SBK/UHN . | HSC . | |
| Stem cell transplant recipients | ✔ | ✔ | ✔ |
| Congenital immunodeficiencies or infants with features suggestive of an undiagnosed immunodeficiency | ✔ | ✔ | ✔ |
| Intrauterine transfusion | ✔ | ✔ | ✔ |
| Premature, low birth weight | ✔ | ✔ | ✔ |
| Term infants (<6 months old old) | ✔ | ✔ | |
| Acute lymphoplastic leukemia | ✔ | ✔ | ✔ |
| Other lymphoid malignancies | ✔ | ✔ | ✔ |
| Acute myeloid leukemia | ✔ | ✔ | |
| Chronic leukemias | ✔ | ✔ | |
| Stem cell donors during harvest | ✔ | ||
| Fludarabine, alemtuzumab, and ATG recipients | ✔ | ✔ | ✔ |
| Children on intensive myeloablative chemotherapy regimens | ✔ | ✔ | |
| Children with solid tumors or malignant hematologic disease | ✔ | ||
| Children with solid organ transplants | ✔ | ||
HSC, Hospital for Sick Children, Toronto, Canada; MGH, Massachusetts General Hospital, Boston, MA; SBK, Sunnybrook Health Sciences Centre, Toronto, Canada; UHN, University Health Network, Toronto, Canada.