Distribution of gene copy number alterations in the studied cohort
| Allelic status . | MYC (8q24) . | Locus (13q14) . | RB1 (13q14) . | ATM (11q23) . | CDKN2A (9p21) . | TP53 (17p13) . | CDK2 (12q13) . | CDK4 (12q14) . | CDKN1B (12p13) . | MDM2 (12q14) . |
|---|---|---|---|---|---|---|---|---|---|---|
| Total interpretable (n) | 130 | 130 | 131 | 129 | 134 | 134 | 116 | 129 | 109 | 114 |
| Diploid locus (n) | 107 | 82 | 96 | 94 | 100 | 104 | 106 | 119 | 93 | 108 |
| Diploid locus (%) | 82% | 63% | 73% | 73% | 75% | 78% | 91% | 92% | 85% | 95% |
| Monoallelic deletion (n) | 0 | 44 | 33 | 31 | 19 | 30 | 1 | 2 | 13 | 2 |
| Monoallelic deletion (%) | 0% | 34% | 25% | 24% | 14% | 22% | 1% | 2% | 12% | 2% |
| Biallelic deletion (n) | 0 | 3 | 1 | 1 | 15 | 0 | 0 | 0 | 0 | 0 |
| Biallelic deletion (%) | 0% | 2% | 1% | 1% | 11% | 0% | 0% | 0% | 0% | 0% |
| Gain (n) | 23 | 1 | 1 | 3 | 0 | 0 | 9 | 8 | 3 | 4 |
| Gain (%) | 18% | 1% | 1% | 2% | 0% | 0% | 8% | 6% | 3% | 4% |
| Total deletions (%) | 0% | 36% | 26% | 25% | 25% | 22% | 1% | 2% | 12% | 2% |
| Total abnormalities (%) | 18% | 37% | 27% | 27% | 25% | 22% | 9% | 8% | 15% | 5% |
| Allelic status . | MYC (8q24) . | Locus (13q14) . | RB1 (13q14) . | ATM (11q23) . | CDKN2A (9p21) . | TP53 (17p13) . | CDK2 (12q13) . | CDK4 (12q14) . | CDKN1B (12p13) . | MDM2 (12q14) . |
|---|---|---|---|---|---|---|---|---|---|---|
| Total interpretable (n) | 130 | 130 | 131 | 129 | 134 | 134 | 116 | 129 | 109 | 114 |
| Diploid locus (n) | 107 | 82 | 96 | 94 | 100 | 104 | 106 | 119 | 93 | 108 |
| Diploid locus (%) | 82% | 63% | 73% | 73% | 75% | 78% | 91% | 92% | 85% | 95% |
| Monoallelic deletion (n) | 0 | 44 | 33 | 31 | 19 | 30 | 1 | 2 | 13 | 2 |
| Monoallelic deletion (%) | 0% | 34% | 25% | 24% | 14% | 22% | 1% | 2% | 12% | 2% |
| Biallelic deletion (n) | 0 | 3 | 1 | 1 | 15 | 0 | 0 | 0 | 0 | 0 |
| Biallelic deletion (%) | 0% | 2% | 1% | 1% | 11% | 0% | 0% | 0% | 0% | 0% |
| Gain (n) | 23 | 1 | 1 | 3 | 0 | 0 | 9 | 8 | 3 | 4 |
| Gain (%) | 18% | 1% | 1% | 2% | 0% | 0% | 8% | 6% | 3% | 4% |
| Total deletions (%) | 0% | 36% | 26% | 25% | 25% | 22% | 1% | 2% | 12% | 2% |
| Total abnormalities (%) | 18% | 37% | 27% | 27% | 25% | 22% | 9% | 8% | 15% | 5% |