Table 2

Hematologic analysis of the spleen and BM of EPCRR84A/R84A mice (n > 4 per group)

Monocyte/macrophage CD11b+B cells B220+Granulocytes Gr-1+Megakaryocytes CD41+HSPC LSK+
Cells/BW (g) × 105Cells/BW (g) × 105%Cells/BW (g) × 105%Cells/BW (g) × 105%Cells/BW (g) × 105%Cells/BW (g) × 105%
Spleen            
 WT 28.0 ± 3.46 1.61 ± 0.32 6.26 ± 1.16 18.2 ± 2.19 65.2 ± 1.07 2.04 ± 0.43 7.14 ± 0.75 2.83 ± 1.12 8.76 ± 2.66 0.70 ± 0.33 0.85 ± 0.32 
 R84A 72.4 ± 14.1 9.81 ± 2.45 12.5 ± 2.24 41.7 ± 9.73 55.0 ± 6.78 4.96 ± 1.04 7.29 ± 1.34 8.91 ± 1.26 12.5 ± 1.79 1.5 ± 1.01 1.5 ± 1.12 
 P .03 .02 .04 .06 .2 .03 .9 .02 .2 .4 .5 
BM            
 WT 23.2 ± 1.02 11.0 ± 1.40 48.3 ± 7.46 5.44 ± 0.46 22.8 ± 2.32 11.4 ± 1.46 50.0 ± 7.65 4.08 ± 1.05 17.1 ± 3.57 0.14 ± 0.04 0.37 ± 0.11 
 R84A 13.2 ± 3.16 5.82 ± 1.45 53.2 ± 3.33 2.19 ± 0.66 19.1 ± 0.99 5.87 ± 1.67 53.1 ± 2.69 2.89 ± 0.34 22.5 ± 3.8 0.15 ± 0.05 0.71 ± 0.27 
 P .03 .02 .54 .01 .10 .04 .72 .18 .36 .8 .3 
Monocyte/macrophage CD11b+B cells B220+Granulocytes Gr-1+Megakaryocytes CD41+HSPC LSK+
Cells/BW (g) × 105Cells/BW (g) × 105%Cells/BW (g) × 105%Cells/BW (g) × 105%Cells/BW (g) × 105%Cells/BW (g) × 105%
Spleen            
 WT 28.0 ± 3.46 1.61 ± 0.32 6.26 ± 1.16 18.2 ± 2.19 65.2 ± 1.07 2.04 ± 0.43 7.14 ± 0.75 2.83 ± 1.12 8.76 ± 2.66 0.70 ± 0.33 0.85 ± 0.32 
 R84A 72.4 ± 14.1 9.81 ± 2.45 12.5 ± 2.24 41.7 ± 9.73 55.0 ± 6.78 4.96 ± 1.04 7.29 ± 1.34 8.91 ± 1.26 12.5 ± 1.79 1.5 ± 1.01 1.5 ± 1.12 
 P .03 .02 .04 .06 .2 .03 .9 .02 .2 .4 .5 
BM            
 WT 23.2 ± 1.02 11.0 ± 1.40 48.3 ± 7.46 5.44 ± 0.46 22.8 ± 2.32 11.4 ± 1.46 50.0 ± 7.65 4.08 ± 1.05 17.1 ± 3.57 0.14 ± 0.04 0.37 ± 0.11 
 R84A 13.2 ± 3.16 5.82 ± 1.45 53.2 ± 3.33 2.19 ± 0.66 19.1 ± 0.99 5.87 ± 1.67 53.1 ± 2.69 2.89 ± 0.34 22.5 ± 3.8 0.15 ± 0.05 0.71 ± 0.27 
 P .03 .02 .54 .01 .10 .04 .72 .18 .36 .8 .3 

BW, body weight.

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