Table 1

Main characteristics of patients from group A and B

All patientsGroup AGroup BP
No. 79 39 40  
Sex ratio, M/F 1.51 1.44 1.67 NS 
Mean age at diagnosis, mo 19 ± 4.9 8.5 ± 3.7 30 ± 8.8 
Protein Ankyrin = 18 Ankyrin = 11 Ankyrin = 7 NS 
Band 3 = 1 Band 3 = 0 Band 3 = 1 
Protein 4.2 = 1 Protein 4.2 = 0 Protein 4.2 = 1 
α-Spectrin = 2 α-Spectrin = 2 α-Spectrin = 0 
β-Spectrin = 12 β-Spectrin = 7 β-Spectrin = 5 
Mean hemoglobin, g/L 97 ± 2.2 83 ± 1.9 110 ± 2.6 **** 
Mean reticulocytes, G/L 392 ± 18 391 ± 26 393 ± 24 NS 
Mean total bilirubin, µmol/L 59 ± 6 47 ± 6.9 68 ± 9 NS 
Mean no. of transfusion per year 1.6 ± 0.4 3.1 ± 0.7 0.13 ± 0.02 **** 
Lithiasis, % 32.1 20.0 47.5 ** 
Mean age at surgery, y 7.4 ± 0.6 4.3 ± 0.6 11 ± 0.7 **** 
Mean time of follow-up, y 11 ± 0.7 12 ± 0.9 9.3 ± 1.0 NS 
All patientsGroup AGroup BP
No. 79 39 40  
Sex ratio, M/F 1.51 1.44 1.67 NS 
Mean age at diagnosis, mo 19 ± 4.9 8.5 ± 3.7 30 ± 8.8 
Protein Ankyrin = 18 Ankyrin = 11 Ankyrin = 7 NS 
Band 3 = 1 Band 3 = 0 Band 3 = 1 
Protein 4.2 = 1 Protein 4.2 = 0 Protein 4.2 = 1 
α-Spectrin = 2 α-Spectrin = 2 α-Spectrin = 0 
β-Spectrin = 12 β-Spectrin = 7 β-Spectrin = 5 
Mean hemoglobin, g/L 97 ± 2.2 83 ± 1.9 110 ± 2.6 **** 
Mean reticulocytes, G/L 392 ± 18 391 ± 26 393 ± 24 NS 
Mean total bilirubin, µmol/L 59 ± 6 47 ± 6.9 68 ± 9 NS 
Mean no. of transfusion per year 1.6 ± 0.4 3.1 ± 0.7 0.13 ± 0.02 **** 
Lithiasis, % 32.1 20.0 47.5 ** 
Mean age at surgery, y 7.4 ± 0.6 4.3 ± 0.6 11 ± 0.7 **** 
Mean time of follow-up, y 11 ± 0.7 12 ± 0.9 9.3 ± 1.0 NS 

F, female; g/L, grams per liter; G/L, giga per liter; M, male; NS, not significant.

*P < .05; **P < .01; ****P < .0001.

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