NHL2 patient characteristics and outcomes by dose level
Patient number . | CAR+ T-cell dose . | Disease histology . | Patient age (years) . | KPS at HCT . | Pre-HSCT disease status . | Deauville score24 before HSCT . | Days to ANC ≥500 . | Best response . | Disease status at data lock . | Time (months) to progression or last follow-up . |
---|---|---|---|---|---|---|---|---|---|---|
2-1 | 50 × 106 | MCL | 57 | 100 | CR1 | 1 | 10 | Continuing CR | Continuing CR | 14.1 |
2-2 | 50 × 106 | DLBCL | 71 | 90 | PR | 3 | 10 | CR | Progressed | 12.6 |
2-3 | 50 × 106 | DLBCL | 57 | 80 | CR2 | 1 | 10 | Continuing CR | Continuing CR | 12.4 |
2-4 | 200 × 106 | MCL | 63 | 100 | CR1 | 1 | 11 | Continuing CR | Continuing CR | 12.3 |
2-5 | 200 × 106 | MCL | 61 | 100 | CR1 | 1 | 11 | Continuing CR | Progressed | 6.4 |
2-6 | 200 × 106 | DLBCL | 67 | 100 | PR | 3 | 10 | CR | CR | 12.2 |
2-7 | 200 × 106 | MCL | 62 | 90 | CR1 | 1 | 12 | Continuing CR | Continuing CR | 12.3 |
2-8 | 200 × 106 | DLBCL | 23 | 90 | CR1 | 4 | 11 | Continuing CR | Continuing CR | 12.5 |
Patient number . | CAR+ T-cell dose . | Disease histology . | Patient age (years) . | KPS at HCT . | Pre-HSCT disease status . | Deauville score24 before HSCT . | Days to ANC ≥500 . | Best response . | Disease status at data lock . | Time (months) to progression or last follow-up . |
---|---|---|---|---|---|---|---|---|---|---|
2-1 | 50 × 106 | MCL | 57 | 100 | CR1 | 1 | 10 | Continuing CR | Continuing CR | 14.1 |
2-2 | 50 × 106 | DLBCL | 71 | 90 | PR | 3 | 10 | CR | Progressed | 12.6 |
2-3 | 50 × 106 | DLBCL | 57 | 80 | CR2 | 1 | 10 | Continuing CR | Continuing CR | 12.4 |
2-4 | 200 × 106 | MCL | 63 | 100 | CR1 | 1 | 11 | Continuing CR | Continuing CR | 12.3 |
2-5 | 200 × 106 | MCL | 61 | 100 | CR1 | 1 | 11 | Continuing CR | Progressed | 6.4 |
2-6 | 200 × 106 | DLBCL | 67 | 100 | PR | 3 | 10 | CR | CR | 12.2 |
2-7 | 200 × 106 | MCL | 62 | 90 | CR1 | 1 | 12 | Continuing CR | Continuing CR | 12.3 |
2-8 | 200 × 106 | DLBCL | 23 | 90 | CR1 | 4 | 11 | Continuing CR | Continuing CR | 12.5 |