Table 1 Patient characteristics and... | American Society of Hematology

Table 1

Patient characteristics and baseline immunologic data

Dose of rhIL-7 (μg/kg)	Patient ID	Age (y)*	Sex	Race	Hispanic	Opportunistic infections	Baseline immune profile†
Dose of rhIL-7 (μg/kg)	Patient ID	Age (y)*	Sex	Race	Hispanic	Opportunistic infections	CD4	CD4%	CD8	CD8%	CD4:CD8	B cells (CD19⁺)	NK cells (CD56⁺CD16⁺)
3	03-001	51	F	White	No	Disseminated histoplasmosis, HPV-related dysplasia	10	2	10	2	1.0	603	140
	03-004	23	F	White	Yes	Severe HPV-related dysplasia	13	3	35	8	0.4	684	104
	03-008	49	F	White	No	VZV	18	4	28	6	0.6	561	163
10	10-001	55	F	White	No	Cryptococcal meningitis, HPV-related dysplasia	52	4	993	77	0.1	297	280
	10-002	70	M	Black	No	Kaposi’s sarcoma	187	36	73	14	2.6	19	61
	10-003	56	F	White	No	Disseminated Cryptococcus, VZV	17	7	24	10	0.7	500	90
	10-005	57	M	White	No	Recurrent oral candidiasis	180	31	139	24	1.3	198	67
	10-006	34	F	White	Yes	VZV, HPV-related dysplasia	23	4	103	18	0.2	931	61
20	20-002	33	F	White	No	Severe refractory plantar warts	15	3	25	5	0.6	704	121

Dose of rhIL-7 (μg/kg)	Patient ID	Age (y)*	Sex	Race	Hispanic	Opportunistic infections	Baseline immune profile†
Dose of rhIL-7 (μg/kg)	Patient ID	Age (y)*	Sex	Race	Hispanic	Opportunistic infections	CD4	CD4%	CD8	CD8%	CD4:CD8	B cells (CD19⁺)	NK cells (CD56⁺CD16⁺)
3	03-001	51	F	White	No	Disseminated histoplasmosis, HPV-related dysplasia	10	2	10	2	1.0	603	140
	03-004	23	F	White	Yes	Severe HPV-related dysplasia	13	3	35	8	0.4	684	104
	03-008	49	F	White	No	VZV	18	4	28	6	0.6	561	163
10	10-001	55	F	White	No	Cryptococcal meningitis, HPV-related dysplasia	52	4	993	77	0.1	297	280
	10-002	70	M	Black	No	Kaposi’s sarcoma	187	36	73	14	2.6	19	61
	10-003	56	F	White	No	Disseminated Cryptococcus, VZV	17	7	24	10	0.7	500	90
	10-005	57	M	White	No	Recurrent oral candidiasis	180	31	139	24	1.3	198	67
	10-006	34	F	White	Yes	VZV, HPV-related dysplasia	23	4	103	18	0.2	931	61
20	20-002	33	F	White	No	Severe refractory plantar warts	15	3	25	5	0.6	704	121

F, female; HPV, human papilloma virus; M, male; NK, natural killer; VZV, varicella zoster virus (shingles).

Age at the time of enrollment.

†

Values reported for CD4, CD8, B cells, and NK cells are in cells per microliter. CD4% and CD8% refer to proportion of CD4⁺ or CD8⁺ cells within the CD3⁺ cell population. Normal ranges are CD4 T cells, 270-2110/μL; % CD4 T cells, 28-72/μL; CD8 T cells, 75-1409/μL; % CD8 T cells, 8-46/μL; CD4:CD8 ratio, 0.70-8.75; B cells (CD19⁺), 38-924/μL; and NK cells (CD3⁺CD16⁺CD56⁺), 40-740/μL.

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