Table 3 Prognostic factors affecting the... | American Society of Hematology

Table 3

Prognostic factors affecting the OS of patients with ATLL

Characteristics	Univariate analysis		Multivariate analysis 1*		Multivariate analysis 2†
Characteristics	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
nPD-L1, positive (vs nPD-L1 negative)	2.455 (1.144-4.642)	.0234	2.373 (1.084-4.625)	.0322
miPD-L1, positive (vs PD-L1 negative)	0.525 (0.341-0.811)	.0039			0.48 1(0.309-0.750)	.0014
JCOG-PI, high (vs low)	1.777 (1.149-2.710)	.0103	1.750 (1.114-2.721)	.0157	1.797 (1.112-2.863)	.0172
Age, >70 (vs ≤70)	1.647 (1.060-2.515)	.0269	1.694 (1.080-2.612)	.0224	1.656 (1.027-2.615)	.0389
Ann Arbor stage, III/IV (vs I/II)	1.776 (0.988-3.530)	.0551	1.640 (0.903-3.283)	.1081	1.829 (0.999-3.687)	.0503
LDH, elevated (vs normal)	1.000 (0.664-1.513)	.9986	0.850 (0.554-1.309)	.4575	0.945 (0.599-1.671)	.8089

Characteristics	Univariate analysis		Multivariate analysis 1*		Multivariate analysis 2†
Characteristics	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
nPD-L1, positive (vs nPD-L1 negative)	2.455 (1.144-4.642)	.0234	2.373 (1.084-4.625)	.0322
miPD-L1, positive (vs PD-L1 negative)	0.525 (0.341-0.811)	.0039			0.48 1(0.309-0.750)	.0014
JCOG-PI, high (vs low)	1.777 (1.149-2.710)	.0103	1.750 (1.114-2.721)	.0157	1.797 (1.112-2.863)	.0172
Age, >70 (vs ≤70)	1.647 (1.060-2.515)	.0269	1.694 (1.080-2.612)	.0224	1.656 (1.027-2.615)	.0389
Ann Arbor stage, III/IV (vs I/II)	1.776 (0.988-3.530)	.0551	1.640 (0.903-3.283)	.1081	1.829 (0.999-3.687)	.0503
LDH, elevated (vs normal)	1.000 (0.664-1.513)	.9986	0.850 (0.554-1.309)	.4575	0.945 (0.599-1.671)	.8089

The variables included in multivariate analysis 1 for OS were nPD-L1, JCOG-PI, age, Ann Arbor stage, and LDH.

The variables included in multivariate analysis 2 for OS were miPD-L1, JCOG-PI, age, Ann Arbor stage, and LDH.