Peripheral blood cell counts
| . | +/+ . | +/− . | −/− . |
|---|---|---|---|
| WBC, K/μL | 8.03 ± 0.72 | 7.95 ± 1.43 | 19.98 ± 1.6* |
| NE, K/μL | 1.29 ± 0.32 | 1.42 ± 0.18 | 2.24 ± 0.5 |
| LY, K/μL | 6.48 ± 0.60 | 6.28 ± 1.53 | 16.49 ± 1.2* |
| MO, K/μL | 0.25 ± 0.12 | 0.22 ± 0.05 | 1.13 ± 0.1* |
| EO, K/μL | 0.00 ± 0.00 | 0.02 ± 0.03 | 0.10 ± 0.1† |
| BA, K/μL | 0.00 ± 0.00 | 0.01 ± 0.01 | 0.03 ± 0.0 |
| NE, % | 16.00 ± 3.29 | 18.38 ± 4.57 | 11.13 ± 1.9 |
| LY, % | 80.76 ± 1.83 | 78.39 ± 5.02 | 82.56 ± 1.5 |
| MO, % | 3.20 ± 1.52 | 2.81 ± 0.32 | 5.65 ± 0.1† |
| EO, % | 0.04 ± 0.01 | 0.32 ± 0.40 | 0.51 ± 0.3 |
| BA, % | 0.00 ± 0.00 | 0.10 ± 0.16 | 0.15 ± 0.2 |
| RBC, M/μL | 10.51 ± 0.33 | 10.89 ± 0.32 | 5.59 ± 0.6* |
| HGB, g/dL | 15.87 ± 0.25 | 15.23 ± 0.46 | 8.90 ± 0.7* |
| HOT, % | 57.57 ± 2.36 | 55.23 ± 2.04 | 33.90 ± 2.4* |
| MCV, fL | 54.77 ± 3.07 | 50.73 ± 1.23 | 60.80 ± 2.2 |
| MCH, Pg | 15.10 ± 0.26 | 14.00 ± 0.35 | 15.97 ± 0.8 |
| MCHC, g/dL | 27.63 ± 1.35 | 27.57 ± 0.25 | 26.23 ± 1.1 |
| RDW, % | 18.03 ± 1.68 | 17.23 ± 0.76 | 35.03 ± 2.7* |
| RETIC, % | 3.92 ± 0.45 | 4.10 ± 0.19 | 66.28 ± 0.2* |
| PLT, K/μL | 816.9 ± 179.2 | 707.0 ± 128.7 | 552.5 ± 131.5† |
| . | +/+ . | +/− . | −/− . |
|---|---|---|---|
| WBC, K/μL | 8.03 ± 0.72 | 7.95 ± 1.43 | 19.98 ± 1.6* |
| NE, K/μL | 1.29 ± 0.32 | 1.42 ± 0.18 | 2.24 ± 0.5 |
| LY, K/μL | 6.48 ± 0.60 | 6.28 ± 1.53 | 16.49 ± 1.2* |
| MO, K/μL | 0.25 ± 0.12 | 0.22 ± 0.05 | 1.13 ± 0.1* |
| EO, K/μL | 0.00 ± 0.00 | 0.02 ± 0.03 | 0.10 ± 0.1† |
| BA, K/μL | 0.00 ± 0.00 | 0.01 ± 0.01 | 0.03 ± 0.0 |
| NE, % | 16.00 ± 3.29 | 18.38 ± 4.57 | 11.13 ± 1.9 |
| LY, % | 80.76 ± 1.83 | 78.39 ± 5.02 | 82.56 ± 1.5 |
| MO, % | 3.20 ± 1.52 | 2.81 ± 0.32 | 5.65 ± 0.1† |
| EO, % | 0.04 ± 0.01 | 0.32 ± 0.40 | 0.51 ± 0.3 |
| BA, % | 0.00 ± 0.00 | 0.10 ± 0.16 | 0.15 ± 0.2 |
| RBC, M/μL | 10.51 ± 0.33 | 10.89 ± 0.32 | 5.59 ± 0.6* |
| HGB, g/dL | 15.87 ± 0.25 | 15.23 ± 0.46 | 8.90 ± 0.7* |
| HOT, % | 57.57 ± 2.36 | 55.23 ± 2.04 | 33.90 ± 2.4* |
| MCV, fL | 54.77 ± 3.07 | 50.73 ± 1.23 | 60.80 ± 2.2 |
| MCH, Pg | 15.10 ± 0.26 | 14.00 ± 0.35 | 15.97 ± 0.8 |
| MCHC, g/dL | 27.63 ± 1.35 | 27.57 ± 0.25 | 26.23 ± 1.1 |
| RDW, % | 18.03 ± 1.68 | 17.23 ± 0.76 | 35.03 ± 2.7* |
| RETIC, % | 3.92 ± 0.45 | 4.10 ± 0.19 | 66.28 ± 0.2* |
| PLT, K/μL | 816.9 ± 179.2 | 707.0 ± 128.7 | 552.5 ± 131.5† |
Peripheral blood cell counts of WT (+/+, n = 3), heterozygous (+/−, n = 3), and dematin FLKO (−/−, n = 3). Values are given as mean ± SD. Unpaired t test. BA, basophils; EO, eosinophils; HCT, hematocrit; HGB, hemoglobin; LY, lymphocytes; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; MO, monocytes, NE, neutrophils; PLT, platelets; RBC, red blood cells; RDW, red cell distribution width; RETIC, reticulocytes; WBC, white blood cells.
P < .001.
P < .05.