Table 1

Goals and standard treatment options for rescue and maintenance therapy

Rescue therapyMaintenance therapy
Goals of treatment Rapid platelet response Durable platelet response 
 Short-term safety Long-term safety and tolerability 
  Patient convenience 
Desired time to response Hours to days Days to weeks 
Standard treatment options Corticosteroids Splenectomy 
 IVIG  
 Anti-D*  
Rescue therapyMaintenance therapy
Goals of treatment Rapid platelet response Durable platelet response 
 Short-term safety Long-term safety and tolerability 
  Patient convenience 
Desired time to response Hours to days Days to weeks 
Standard treatment options Corticosteroids Splenectomy 
 IVIG  
 Anti-D*  

IVIG, intravenous immunoglobulin G.

*

Indicated only in Rh(D)-positive, nonsplenectomized patients.

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