ISTH-DIC scoring system
| Risk assessment: Does the patient have an underlying disorder known to be associated with overt DIC | 
| If yes, proceed; if no, do not use this algorithm | 
| Order global coagulation tests (platelet count, PT, fibrinogen, soluble fibrin monomers, or fibrin degradation products) | 
| Score global coagulation test results | 
| Platelet count (>100 × 109/L, 0; <100, 1; <50, 2) | 
| Elevated fibrin-related marker (eg, soluble fibrin monomers/fibrin degradation products) (no increase = 0; moderate increase = 2; strong increase = 3) | 
| Prolonged PT (<3 s, 0; >3 s but <6 s, 1, >6 s, 2) | 
| Fibrinogen level (>1.0 g/L = 0; <1.0 g/L = 1) | 
| Calculate score | 
| If ≥5, compatible with overt DIC | 
| Risk assessment: Does the patient have an underlying disorder known to be associated with overt DIC | 
| If yes, proceed; if no, do not use this algorithm | 
| Order global coagulation tests (platelet count, PT, fibrinogen, soluble fibrin monomers, or fibrin degradation products) | 
| Score global coagulation test results | 
| Platelet count (>100 × 109/L, 0; <100, 1; <50, 2) | 
| Elevated fibrin-related marker (eg, soluble fibrin monomers/fibrin degradation products) (no increase = 0; moderate increase = 2; strong increase = 3) | 
| Prolonged PT (<3 s, 0; >3 s but <6 s, 1, >6 s, 2) | 
| Fibrinogen level (>1.0 g/L = 0; <1.0 g/L = 1) | 
| Calculate score | 
| If ≥5, compatible with overt DIC |