Clinical characteristics of the VEBIOS discovery study
| . | 89 Cases . | 88 Controls . | ||
|---|---|---|---|---|
| Variables . | N . | Freq. . | N . | Freq. . |
| Localization of the thrombosis | ||||
| DVT, lower limbs | 47 | 0.53 | ||
| Proximal | 36 | 0.77 | ||
| PE | 45 | 0.51 | ||
| Gender and biometry | ||||
| Gender, women | 35 | 0.39 | 35 | 0.39 |
| Age, y (mean ± SD and range) | 51.1 ± 10.8 | (20-70) | 51.6 ± 10.8 | (21-70) |
| BMI, kg/m2 (mean ± SD and range) | 26.7 ± 4.6 | (17-46) | 25.6 ± 4 | (19-38) |
| Obese, BMI ≥ 30 kg/m2 | 20 | 0.22 | 16 | 0.19 |
| Cardiovascular risk factors | ||||
| Hypertension* | 19 | 0.21 | 10 | 0.11 |
| Hyperlipidemia* | 5 | 0.06 | 5 | 0.06 |
| Diabetes mellitus* | 2 | 0.02 | 5 | 0.06 |
| Current smoking† | 15 | 0.17 | 7 | 0.08 |
| Family history | ||||
| VTE, first-degree relative <60 y old | 15 | 0.17 | 1 | 0.01 |
| Provoked risk factors‡ | 39 | 0.44 | 17 | 0.19 |
| Trauma | 22 | 0.22 | 7 | 0.08 |
| Cast, orthosis, etc | 15 | 0.17 | 1 | 0.01 |
| Surgery | 16 | 0.18 | 2 | 0.02 |
| Pregnancy, postpartum 3 mo | 0 | 0 | 0 | 0 |
| Contraceptives§ | 11 | 0.31 | 9 | 0.26 |
| Menopausal replacement therapy# | 5 | 0.14 | 1 | 0.03 |
| . | 89 Cases . | 88 Controls . | ||
|---|---|---|---|---|
| Variables . | N . | Freq. . | N . | Freq. . |
| Localization of the thrombosis | ||||
| DVT, lower limbs | 47 | 0.53 | ||
| Proximal | 36 | 0.77 | ||
| PE | 45 | 0.51 | ||
| Gender and biometry | ||||
| Gender, women | 35 | 0.39 | 35 | 0.39 |
| Age, y (mean ± SD and range) | 51.1 ± 10.8 | (20-70) | 51.6 ± 10.8 | (21-70) |
| BMI, kg/m2 (mean ± SD and range) | 26.7 ± 4.6 | (17-46) | 25.6 ± 4 | (19-38) |
| Obese, BMI ≥ 30 kg/m2 | 20 | 0.22 | 16 | 0.19 |
| Cardiovascular risk factors | ||||
| Hypertension* | 19 | 0.21 | 10 | 0.11 |
| Hyperlipidemia* | 5 | 0.06 | 5 | 0.06 |
| Diabetes mellitus* | 2 | 0.02 | 5 | 0.06 |
| Current smoking† | 15 | 0.17 | 7 | 0.08 |
| Family history | ||||
| VTE, first-degree relative <60 y old | 15 | 0.17 | 1 | 0.01 |
| Provoked risk factors‡ | 39 | 0.44 | 17 | 0.19 |
| Trauma | 22 | 0.22 | 7 | 0.08 |
| Cast, orthosis, etc | 15 | 0.17 | 1 | 0.01 |
| Surgery | 16 | 0.18 | 2 | 0.02 |
| Pregnancy, postpartum 3 mo | 0 | 0 | 0 | 0 |
| Contraceptives§ | 11 | 0.31 | 9 | 0.26 |
| Menopausal replacement therapy# | 5 | 0.14 | 1 | 0.03 |