Multivariate analysis
| Variables . | HR . | 95% CI . | P value . |
|---|---|---|---|
| OS | |||
| Patient age | 1.01 | 1.01-1.02 | <.001 |
| Donor age | 1.01 | 1.00-1.02 | .002 |
| Intermediate disease stage | 1.18 | 1.00-1.40 | .049 |
| Advanced disease stage | 1.79 | 1.53-2.10 | <.001 |
| HLA 9/10 | 1.21 | 1.04-1.39 | .011 |
| HLA 8/10 | 1.47 | 1.13-1.90 | .004 |
| Recipient CMV− − donor CMV+ | 1.31 | 1.06-1.63 | .013 |
| KPS < 80 | 1.75 | 1.35-2.27 | <.001 |
| 10/10 HLA, MICA-129 mismatched | 1.77 | 1.22-2.57 | .003 |
| 9/10 HLA, MICA-129 mismatched | 1.19 | 0.84-1.68 | .327 |
| 8/10 HLA, MICA-129 mismatched | 1.37 | 0.76-2.44 | .295 |
| DFS | |||
| Patient age | 1.01 | 1.01-1.02 | <.001 |
| Donor age | 1.01 | 1.00-1.01 | .013 |
| Intermediate disease stage | 1.30 | 1.11-1.51 | <.001 |
| Advanced disease stage | 1.87 | 1.61-2.17 | <.001 |
| HLA 9/10 | 1.18 | 1.03-1.35 | .015 |
| HLA 8/10 | 1.34 | 1.04-1.71 | .022 |
| Recipient CMV− − donor CMV+ | 1.29 | 1.06-1.58 | .013 |
| KPS < 80 | 1.79 | 1.40-2.30 | <.001 |
| 10/10 HLA, MICA-129 mismatched | 1.77 | 1.26-2.50 | .001 |
| 9/10 HLA, MICA-129 mismatched | 1.08 | 0.77-1.50 | .657 |
| 8/10 HLA, MICA-129 mismatched | 1.64 | 0.96-2.80 | .068 |
| Variables . | HR . | 95% CI . | P value . |
|---|---|---|---|
| OS | |||
| Patient age | 1.01 | 1.01-1.02 | <.001 |
| Donor age | 1.01 | 1.00-1.02 | .002 |
| Intermediate disease stage | 1.18 | 1.00-1.40 | .049 |
| Advanced disease stage | 1.79 | 1.53-2.10 | <.001 |
| HLA 9/10 | 1.21 | 1.04-1.39 | .011 |
| HLA 8/10 | 1.47 | 1.13-1.90 | .004 |
| Recipient CMV− − donor CMV+ | 1.31 | 1.06-1.63 | .013 |
| KPS < 80 | 1.75 | 1.35-2.27 | <.001 |
| 10/10 HLA, MICA-129 mismatched | 1.77 | 1.22-2.57 | .003 |
| 9/10 HLA, MICA-129 mismatched | 1.19 | 0.84-1.68 | .327 |
| 8/10 HLA, MICA-129 mismatched | 1.37 | 0.76-2.44 | .295 |
| DFS | |||
| Patient age | 1.01 | 1.01-1.02 | <.001 |
| Donor age | 1.01 | 1.00-1.01 | .013 |
| Intermediate disease stage | 1.30 | 1.11-1.51 | <.001 |
| Advanced disease stage | 1.87 | 1.61-2.17 | <.001 |
| HLA 9/10 | 1.18 | 1.03-1.35 | .015 |
| HLA 8/10 | 1.34 | 1.04-1.71 | .022 |
| Recipient CMV− − donor CMV+ | 1.29 | 1.06-1.58 | .013 |
| KPS < 80 | 1.79 | 1.40-2.30 | <.001 |
| 10/10 HLA, MICA-129 mismatched | 1.77 | 1.26-2.50 | .001 |
| 9/10 HLA, MICA-129 mismatched | 1.08 | 0.77-1.50 | .657 |
| 8/10 HLA, MICA-129 mismatched | 1.64 | 0.96-2.80 | .068 |
Age was modeled as continuous variable.