Table 2.

Treatment modalities

Treated patients (N = 37)
Chemotherapy adapted to the clone, n (%) 29 (78%) 
 Median time to treatment, mo 3 (1-20) 
 Alkylating agent-dexamethasone* 5 (17%) 
 Bortezomib based regimen-dexamethasone 22 (76%) 
 Prednisone-rituximab 2 (7%) 
Immunosuppressive therapy, n 8 (22%) 
 Median time to treatment, mo 4 (1-54) 
 Prednisone-dexamethasone 4 (50%) 
 Prednisone-cyclophosphamide 1 (12.5%) 
 Prednisone-rituximab 1 (12.5%) 
 Prednisone-mycophenolate mofetil 1 (12.5%) 
 Prednisone-azathioprine 1 (12.5%) 
Treated patients (N = 37)
Chemotherapy adapted to the clone, n (%) 29 (78%) 
 Median time to treatment, mo 3 (1-20) 
 Alkylating agent-dexamethasone* 5 (17%) 
 Bortezomib based regimen-dexamethasone 22 (76%) 
 Prednisone-rituximab 2 (7%) 
Immunosuppressive therapy, n 8 (22%) 
 Median time to treatment, mo 4 (1-54) 
 Prednisone-dexamethasone 4 (50%) 
 Prednisone-cyclophosphamide 1 (12.5%) 
 Prednisone-rituximab 1 (12.5%) 
 Prednisone-mycophenolate mofetil 1 (12.5%) 
 Prednisone-azathioprine 1 (12.5%) 

*Cyclophosphamide-dexamethasone (n = 4), Melphalan-dexamethasone (n = 2).

Bortezomib-dexamethasone (n = 10), bortezomib-thalidomide-dexamethasone (n=2), bortezomib-cyclophosphamide-dexamethasone (n = 10).

For treatment of chronic lymphoid leukemia.

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