Patient characteristics at diagnosis
| Characteristics (N = 187) . | Number (%) . | Median (range) . |
|---|---|---|
| Age, y | 50 (14-84) | |
| ≥60 | 52 (28) | |
| Sex | ||
| Male | 97 (52) | |
| Female | 90 (48) | |
| Risk category | ||
| High-risk | 54 (29) | |
| Low-risk | 133 (71) | |
| Leukocyte count (×109/L) | 2.2 (0.3-187.9) | |
| Platelet count (×109/L) | 36 (3-261) | |
| Cytogenetics | ||
| t(15;17) | 122 (65) | |
| t(15;17) + other cytogenetic abnormalities | 45 (24) | |
| Diploid (RT-PCR +) | 10 (5) | |
| Not done/insufficient metaphases (RT-PCR+) | 9 (5) | |
| Hyperdiploid (RT-PCR +) | 1 (0.5) | |
| FAB morphology | ||
| M3 | 163 (87) | |
| M3v | 22 (12) | |
| Unknown | 2 (1) | |
| PML-RARA isoforms | ||
| Short | 78 (42) | |
| Long | 105 (56) | |
| Both | 4 (2) |
| Characteristics (N = 187) . | Number (%) . | Median (range) . |
|---|---|---|
| Age, y | 50 (14-84) | |
| ≥60 | 52 (28) | |
| Sex | ||
| Male | 97 (52) | |
| Female | 90 (48) | |
| Risk category | ||
| High-risk | 54 (29) | |
| Low-risk | 133 (71) | |
| Leukocyte count (×109/L) | 2.2 (0.3-187.9) | |
| Platelet count (×109/L) | 36 (3-261) | |
| Cytogenetics | ||
| t(15;17) | 122 (65) | |
| t(15;17) + other cytogenetic abnormalities | 45 (24) | |
| Diploid (RT-PCR +) | 10 (5) | |
| Not done/insufficient metaphases (RT-PCR+) | 9 (5) | |
| Hyperdiploid (RT-PCR +) | 1 (0.5) | |
| FAB morphology | ||
| M3 | 163 (87) | |
| M3v | 22 (12) | |
| Unknown | 2 (1) | |
| PML-RARA isoforms | ||
| Short | 78 (42) | |
| Long | 105 (56) | |
| Both | 4 (2) |
FAB, French-American-British.