Multivariate analysis on the effect of prophylaxis on the repeated measures of overall joint ROM over time in 2908 US hemophilia participants aged 2 to 19 years
| . | Initial ROM status . | Rate of ROM change . | ||
|---|---|---|---|---|
| Covariates . | Parameter estimate . | P . | Parameter estimate . | P . |
| Age | −0.85 | <.001 | — | — |
| Race: white vs others | 1.56 | <.001 | — | — |
| Inhibitor: yes vs no | −0.46 | .06 | — | — |
| BMI: ≥85th vs <85th percentile | −1.07 | .003 | −0.09 | .001 |
| Primary prophy <4 y: yes vs no | 0.96 | .24 | 0.20 | .03 |
| Primary prophy 4 or 5 y: yes vs no | 0.92 | .34 | 0.10 | .29 |
| Secondary prophy: yes vs no | 0.54 | .46 | 0.04 | .36 |
| . | Initial ROM status . | Rate of ROM change . | ||
|---|---|---|---|---|
| Covariates . | Parameter estimate . | P . | Parameter estimate . | P . |
| Age | −0.85 | <.001 | — | — |
| Race: white vs others | 1.56 | <.001 | — | — |
| Inhibitor: yes vs no | −0.46 | .06 | — | — |
| BMI: ≥85th vs <85th percentile | −1.07 | .003 | −0.09 | .001 |
| Primary prophy <4 y: yes vs no | 0.96 | .24 | 0.20 | .03 |
| Primary prophy 4 or 5 y: yes vs no | 0.92 | .34 | 0.10 | .29 |
| Secondary prophy: yes vs no | 0.54 | .46 | 0.04 | .36 |
Prophy, prophylaxis.