Genomic characteristics of primary AML specimens used for PDX model studies
| PDX USI . | Disease status . | Leukemia cytogenetics and molecular lesions . |
|---|---|---|
| AML290 | De novo | 46,XX,der(10)t(8;10)(q11.1;p15);13q LOH KMT2A partial tandem duplication |
| JMML117 | De novo | 45,XY,-7; PTPN11 G503V |
| PDX USI . | Disease status . | Leukemia cytogenetics and molecular lesions . |
|---|---|---|
| AML290 | De novo | 46,XX,der(10)t(8;10)(q11.1;p15);13q LOH KMT2A partial tandem duplication |
| JMML117 | De novo | 45,XY,-7; PTPN11 G503V |
Both AML specimens were CD52 negative by flow cytometry.
LOH, loss of heterozygosity; USI, unique specimen identifier.