Multivariate analysis of factors affecting CD34 mobilization yields
Covariate . | F value . | P value . |
---|---|---|
Age of donor | 9.44 | .0051 |
Baseline CD34 | 27.35 | <.0001 |
% pDC in product | 5.81 | .024 |
Baseline platelets | 11.64 | .0022 |
AUC of plerixafor | 5.63 | .026 |
Covariate . | F value . | P value . |
---|---|---|
Age of donor | 9.44 | .0051 |
Baseline CD34 | 27.35 | <.0001 |
% pDC in product | 5.81 | .024 |
Baseline platelets | 11.64 | .0022 |
AUC of plerixafor | 5.63 | .026 |
A repeated measures regression model of CD34/L undergoing apheresis day 1 transformed to log10 by demographic and clinical variables was performed. Cellular mobilization over time was analyzed by mixed models (transformation shown in parentheses) specifying patient as a random effect and modeling the outcome of CD34/L day 1 on a log10 scale. Factors reaching significance at the P < .1 level were carried forward to the multivariate analysis.