Multivariate Cox proportional hazards models of the association of CNA presence and clinical variables with survival
| CNAs, n . | OS* . | EFS* . | RR† . | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patients, n . | HR . | 95% CI . | P . | Patients, n . | HR . | 95% CI . | P . | Patients, n . | HR . | 95% CI . | P . | |
| Overall | ||||||||||||
| 0 | 181 | 1 | — | — | 181 | 1 | — | — | 146 | 1 | — | — |
| 1+ | 252 | 1.7 | 1.2-2.4 | .005 | 251 | 1.4 | 1.0-1.8 | .029 | 203 | 1.4 | 1.0-2.0 | .043 |
| Favorable risk | ||||||||||||
| 0 | 87 | 1 | — | — | 87 | 1 | — | — | 78 | 1 | — | — |
| 1+ | 100 | 1.5 | 0.7-3.1 | .286 | 100 | 1.1 | 0.7-1.8 | .709 | 87 | 1.0 | 0.6-1.8 | .885 |
| Standard risk | ||||||||||||
| 0 | 60 | 1 | — | — | 60 | 1 | — | — | 44 | 1 | — | — |
| 1+ | 114 | 1.9 | 1.1-3.3 | .021 | 114 | 1.7 | 1.1-2.6 | .020 | 88 | 1.5 | 0.9-2.6 | .105 |
| Poor risk | ||||||||||||
| 0 | 27 | 1 | — | — | 27 | 1 | — | — | 20 | 1 | — | — |
| 1+ | 31 | 1.7 | 0.8-3.6 | .193 | 31 | 1.4 | 0.7-2.6 | .374 | 21 | 1.6 | 0.7-4.0 | .278 |
| CNAs, n . | OS* . | EFS* . | RR† . | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patients, n . | HR . | 95% CI . | P . | Patients, n . | HR . | 95% CI . | P . | Patients, n . | HR . | 95% CI . | P . | |
| Overall | ||||||||||||
| 0 | 181 | 1 | — | — | 181 | 1 | — | — | 146 | 1 | — | — |
| 1+ | 252 | 1.7 | 1.2-2.4 | .005 | 251 | 1.4 | 1.0-1.8 | .029 | 203 | 1.4 | 1.0-2.0 | .043 |
| Favorable risk | ||||||||||||
| 0 | 87 | 1 | — | — | 87 | 1 | — | — | 78 | 1 | — | — |
| 1+ | 100 | 1.5 | 0.7-3.1 | .286 | 100 | 1.1 | 0.7-1.8 | .709 | 87 | 1.0 | 0.6-1.8 | .885 |
| Standard risk | ||||||||||||
| 0 | 60 | 1 | — | — | 60 | 1 | — | — | 44 | 1 | — | — |
| 1+ | 114 | 1.9 | 1.1-3.3 | .021 | 114 | 1.7 | 1.1-2.6 | .020 | 88 | 1.5 | 0.9-2.6 | .105 |
| Poor risk | ||||||||||||
| 0 | 27 | 1 | — | — | 27 | 1 | — | — | 20 | 1 | — | — |
| 1+ | 31 | 1.7 | 0.8-3.6 | .193 | 31 | 1.4 | 0.7-2.6 | .374 | 21 | 1.6 | 0.7-4.0 | .278 |