Drug-related AEs in at least 5% of patients
| AE . | G1-G2 . | G3-G4 . | ||
|---|---|---|---|---|
| N . | % . | N . | % . | |
| Platelet count decreased | 6 | 24 | 5 | 20 |
| Anemia | 5 | 20 | 5 | 20 |
| Neutrophil count decreased | 4 | 16 | 5 | 20 |
| Cough | 7 | 28 | 0 | 0 |
| Dyspnea | 4 | 16 | 2 | 8 |
| Fatigue | 3 | 12 | 2 | 8 |
| Nausea | 5 | 20 | 0 | 0 |
| Diarrhea | 3 | 12 | 0 | 0 |
| Vomiting | 3 | 12 | 0 | 0 |
| Febrile neutropenia | 0 | 0 | 2 | 8 |
| Chills | 2 | 8 | 0 | 0 |
| Fever | 1 | 4 | 1 | 4 |
| Hypoxia | 0 | 0 | 2 | 8 |
| Rash maculo-papular | 1 | 4 | 1 | 4 |
| AE . | G1-G2 . | G3-G4 . | ||
|---|---|---|---|---|
| N . | % . | N . | % . | |
| Platelet count decreased | 6 | 24 | 5 | 20 |
| Anemia | 5 | 20 | 5 | 20 |
| Neutrophil count decreased | 4 | 16 | 5 | 20 |
| Cough | 7 | 28 | 0 | 0 |
| Dyspnea | 4 | 16 | 2 | 8 |
| Fatigue | 3 | 12 | 2 | 8 |
| Nausea | 5 | 20 | 0 | 0 |
| Diarrhea | 3 | 12 | 0 | 0 |
| Vomiting | 3 | 12 | 0 | 0 |
| Febrile neutropenia | 0 | 0 | 2 | 8 |
| Chills | 2 | 8 | 0 | 0 |
| Fever | 1 | 4 | 1 | 4 |
| Hypoxia | 0 | 0 | 2 | 8 |
| Rash maculo-papular | 1 | 4 | 1 | 4 |
Decisions on whether the AE was related to the study drug were made by the treating physicians/investigators. A more detailed list of all AEs is provided in supplemental Table 1. n = 25.