AEs
. | Grade . | ||||||
---|---|---|---|---|---|---|---|
1 . | 2 . | 3 . | 4 . | 5 . | ≥3 . | Any grade . | |
Hematologic toxicity | |||||||
Neutropenia | 8 | 18 | 58 | 12 | — | 70 | 96 |
Leukopenia | 10 | 38 | 34 | 2 | — | 36 | 84 |
Thrombocytopenia | 56 | 22 | 4 | — | — | 4 | 82 |
Anemia | 36 | 34 | 4 | — | — | 4 | 74 |
Lymphopenia | — | 16 | 10 | 10 | — | 20 | 36 |
Nonhematologic toxicity | |||||||
Fatigue | 30 | 38 | 4 | — | — | 4 | 72 |
Peripheral neuropathy | 46 | 18 | 4 | — | — | 4 | 68 |
Diarrhea | 36 | 10 | 2 | — | — | 2 | 48 |
Nausea/vomiting | 40 | 2 | — | — | — | — | 42 |
Lung infection | — | 6 | 8 | 2 | — | 10 | 16 |
Thromboembolic event | 10 | — | — | — | — | — | 10 |
Dyspnea | 2 | 4 | 2 | — | — | 2 | 8 |
Insomnia | — | 8 | — | — | — | — | 8 |
Herpes zoster infection | 2 | 2 | 2 | — | — | 2 | 6 |
Generalized muscle weakness | — | 6 | — | — | — | — | 6 |
Dizziness | — | 6 | — | — | — | — | 6 |
Anxiety | — | — | 4 | — | — | 4 | 4 |
Edema | — | 2 | 2 | — | — | 2 | 4 |
Constipation | — | 4 | — | — | — | — | 4 |
. | Grade . | ||||||
---|---|---|---|---|---|---|---|
1 . | 2 . | 3 . | 4 . | 5 . | ≥3 . | Any grade . | |
Hematologic toxicity | |||||||
Neutropenia | 8 | 18 | 58 | 12 | — | 70 | 96 |
Leukopenia | 10 | 38 | 34 | 2 | — | 36 | 84 |
Thrombocytopenia | 56 | 22 | 4 | — | — | 4 | 82 |
Anemia | 36 | 34 | 4 | — | — | 4 | 74 |
Lymphopenia | — | 16 | 10 | 10 | — | 20 | 36 |
Nonhematologic toxicity | |||||||
Fatigue | 30 | 38 | 4 | — | — | 4 | 72 |
Peripheral neuropathy | 46 | 18 | 4 | — | — | 4 | 68 |
Diarrhea | 36 | 10 | 2 | — | — | 2 | 48 |
Nausea/vomiting | 40 | 2 | — | — | — | — | 42 |
Lung infection | — | 6 | 8 | 2 | — | 10 | 16 |
Thromboembolic event | 10 | — | — | — | — | — | 10 |
Dyspnea | 2 | 4 | 2 | — | — | 2 | 8 |
Insomnia | — | 8 | — | — | — | — | 8 |
Herpes zoster infection | 2 | 2 | 2 | — | — | 2 | 6 |
Generalized muscle weakness | — | 6 | — | — | — | — | 6 |
Dizziness | — | 6 | — | — | — | — | 6 |
Anxiety | — | — | 4 | — | — | 4 | 4 |
Edema | — | 2 | 2 | — | — | 2 | 4 |
Constipation | — | 4 | — | — | — | — | 4 |
Values are reported as percentage of patients. All AEs with attribution of possible, probable, or definite occurring in >1 patient are listed.
—, Not applicable.