Response
| Parameter . | Overall, n (%) . | Decitabine, n (%) . | Azacitidine, n (%) . | P . |
|---|---|---|---|---|
| Morphologic response, N | 109 | 70 | 39 | |
| CR | 40 (37) | 26 (37) | 14 (36) | |
| mCR | 8 (7) | 6 (9) | 2 (5) | |
| HI | 20 (18) | 17 (24) | 3 (8) | |
| Overall | 68 (62) | 49 (70) | 19 (49) | .03 |
| Transfusion response, N | 57 | 38 | 19 | |
| RBC | 11/46 (24) | 8/29 (28) | 3/17 (18) | |
| Platelets | 3/5 (60) | 3/4 (75) | 0/1 | |
| RBC + Platelets | 1/6 (17) | 1/5 (20) | 0/1 | |
| Overall | 15 (26) | 12 (32) | 3 (16) | .2 |
| Cytogenetic response, N | 44 | 28 | 16 | |
| Complete | 8 (18) | 7 (25) | 1 (6) | |
| Partial | 13 (30) | 10 (36) | 3 (19) | |
| Overall | 21 (48) | 17 (61) | 4 (25) | .02 |
| Morphologic response (BM blasts ≥5%), N | 32 | 21 | 11 | |
| CR | 14 (44) | 12 (57) | 2 (18) | |
| mCR | 8 (25) | 6 (29) | 2 (18) | |
| HI | 3 (9) | 3 (14) | 0 | |
| Overall | 25 (78) | 21 (100) | 4 (36) | <.001 |
| Hematologic response (BM blasts <5%), N | 72 | 45 | 27 | |
| ≥1 lineage | 29 (40) | 16 (36) | 13 (48) | |
| All lineages | 17 (24) | 10 (22) | 7 (26) |
| Parameter . | Overall, n (%) . | Decitabine, n (%) . | Azacitidine, n (%) . | P . |
|---|---|---|---|---|
| Morphologic response, N | 109 | 70 | 39 | |
| CR | 40 (37) | 26 (37) | 14 (36) | |
| mCR | 8 (7) | 6 (9) | 2 (5) | |
| HI | 20 (18) | 17 (24) | 3 (8) | |
| Overall | 68 (62) | 49 (70) | 19 (49) | .03 |
| Transfusion response, N | 57 | 38 | 19 | |
| RBC | 11/46 (24) | 8/29 (28) | 3/17 (18) | |
| Platelets | 3/5 (60) | 3/4 (75) | 0/1 | |
| RBC + Platelets | 1/6 (17) | 1/5 (20) | 0/1 | |
| Overall | 15 (26) | 12 (32) | 3 (16) | .2 |
| Cytogenetic response, N | 44 | 28 | 16 | |
| Complete | 8 (18) | 7 (25) | 1 (6) | |
| Partial | 13 (30) | 10 (36) | 3 (19) | |
| Overall | 21 (48) | 17 (61) | 4 (25) | .02 |
| Morphologic response (BM blasts ≥5%), N | 32 | 21 | 11 | |
| CR | 14 (44) | 12 (57) | 2 (18) | |
| mCR | 8 (25) | 6 (29) | 2 (18) | |
| HI | 3 (9) | 3 (14) | 0 | |
| Overall | 25 (78) | 21 (100) | 4 (36) | <.001 |
| Hematologic response (BM blasts <5%), N | 72 | 45 | 27 | |
| ≥1 lineage | 29 (40) | 16 (36) | 13 (48) | |
| All lineages | 17 (24) | 10 (22) | 7 (26) |
HI, hematologic improvement; RBC, red blood cell.