Outcome of bleeding management with PCCs
| . | Apixaban . | Rivaroxaban . | ||
|---|---|---|---|---|
| Effective . | Ineffective . | Effective . | Ineffective . | |
| Bleeding location, n (%) | ||||
| ICH | 21 (72.4) | 8 (27.6) | 22 (73.3) | 8 (26.7) |
| GI | 3 (60.0) | 2 (40.0) | 5 (62.5) | 3 (37.5) |
| Visceral | 0 (0.0) | 2 (100.0) | 1 (33.3) | 2 (66.7) |
| Genitourinary | 1 (50.0) | 1 (50.0) | 2 (100.0) | 0 (0.0) |
| Musculoskeletal | 1 (100.0) | 0 (0.0) | 2 (100.0) | 0 (0.0) |
| Hemoglobin drop, n (%) | 2 (33.3) | 4 (66.7) | 3 (37.5) | 5 (62.5) |
| Any invasive procedure, n (%) | ||||
| None | 17 (68.0) | 8 (32.0) | 23 (74.2) | 1 (25.0) |
| Craniotomy | 5 (71.4)* | 2 (28.6) | 6 (100.0)* | 0 (0.0) |
| Gastroscopy | 3 (75.1)† | 1 (25.0) | 1 (33.3)† | 2 (66.7) |
| Embolization | 0 (0.0) | 2 (100.0) | 1 (50.0)* | 1 (50.0) |
| Fasciotomy | 1 (100.0)* | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| Laparotomy | 0 (0.0) | 0 (0.0) | 1 (50.0) | 1 (50.0) |
| Thoracotomy | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (100.0) |
| Length of hospital stay, d, median (IQR) | 7.0 (3.0-15.0) | 4.5 (2.0-7.0) | 9.0 (4.0-16.0) | 2.5 (2.0-5.0) |
| Discharge destination, n (%) | ||||
| Home | 14 (93.3) | 1 (6.7) | 10 (90.9) | 1 (9.1) |
| Rehabilitation facility | 7 (63.6) | 4 (36.4) | 13 (92.9) | 1 (7.1) |
| Other hospital | 2 (66.7) | 1 (33.3) | 1 (100.0) | 0 (0.0) |
| Deceased | 3 (33.3) | 6 (66.7) | 5 (35.7) | 9 (64.3) |
| Unknown | 0 (0.0) | 1 (100.0) | 1 (33.3) | 2 (66.7) |
| Total | 26 | 13 | 32 | 13 |
| . | Apixaban . | Rivaroxaban . | ||
|---|---|---|---|---|
| Effective . | Ineffective . | Effective . | Ineffective . | |
| Bleeding location, n (%) | ||||
| ICH | 21 (72.4) | 8 (27.6) | 22 (73.3) | 8 (26.7) |
| GI | 3 (60.0) | 2 (40.0) | 5 (62.5) | 3 (37.5) |
| Visceral | 0 (0.0) | 2 (100.0) | 1 (33.3) | 2 (66.7) |
| Genitourinary | 1 (50.0) | 1 (50.0) | 2 (100.0) | 0 (0.0) |
| Musculoskeletal | 1 (100.0) | 0 (0.0) | 2 (100.0) | 0 (0.0) |
| Hemoglobin drop, n (%) | 2 (33.3) | 4 (66.7) | 3 (37.5) | 5 (62.5) |
| Any invasive procedure, n (%) | ||||
| None | 17 (68.0) | 8 (32.0) | 23 (74.2) | 1 (25.0) |
| Craniotomy | 5 (71.4)* | 2 (28.6) | 6 (100.0)* | 0 (0.0) |
| Gastroscopy | 3 (75.1)† | 1 (25.0) | 1 (33.3)† | 2 (66.7) |
| Embolization | 0 (0.0) | 2 (100.0) | 1 (50.0)* | 1 (50.0) |
| Fasciotomy | 1 (100.0)* | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| Laparotomy | 0 (0.0) | 0 (0.0) | 1 (50.0) | 1 (50.0) |
| Thoracotomy | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (100.0) |
| Length of hospital stay, d, median (IQR) | 7.0 (3.0-15.0) | 4.5 (2.0-7.0) | 9.0 (4.0-16.0) | 2.5 (2.0-5.0) |
| Discharge destination, n (%) | ||||
| Home | 14 (93.3) | 1 (6.7) | 10 (90.9) | 1 (9.1) |
| Rehabilitation facility | 7 (63.6) | 4 (36.4) | 13 (92.9) | 1 (7.1) |
| Other hospital | 2 (66.7) | 1 (33.3) | 1 (100.0) | 0 (0.0) |
| Deceased | 3 (33.3) | 6 (66.7) | 5 (35.7) | 9 (64.3) |
| Unknown | 0 (0.0) | 1 (100.0) | 1 (33.3) | 2 (66.7) |
| Total | 26 | 13 | 32 | 13 |