Table 4.

Characteristics of patients with thromboembolic events after treatment with PCCs

Age, ySexAnticoagulantDoseIndicationBleedingPCC dose, IU (IU/kg)ThromboembolismTiming from PCC, dOutcome
80 Female Rivaroxaban 20 mg × 1 SPAF ICH 1500 (29) Stroke 10 Discharged. Died after 112 d of new stroke. 
71 Female Apixaban 5 mg × 2 SPAF ICH 2000 (27) Stroke Died after 18 d from ICH. 
73 Male Rivaroxaban 20 mg × 1 SPAF ICH 2000 (27) Suspected PE* 15 Died after 16 d from ICH. 
Age, ySexAnticoagulantDoseIndicationBleedingPCC dose, IU (IU/kg)ThromboembolismTiming from PCC, dOutcome
80 Female Rivaroxaban 20 mg × 1 SPAF ICH 1500 (29) Stroke 10 Discharged. Died after 112 d of new stroke. 
71 Female Apixaban 5 mg × 2 SPAF ICH 2000 (27) Stroke Died after 18 d from ICH. 
73 Male Rivaroxaban 20 mg × 1 SPAF ICH 2000 (27) Suspected PE* 15 Died after 16 d from ICH. 
*

Diagnosis of pulmonary embolism was suspected clinically but never verified on imaging.

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