Summarized findings of prospective studies that examined the impact of CGA on treatment outcomes in elderly patients with DLBCL
Reference . | No. of patients . | Location . | Age (y) . | . | . | OS (%) . | ORR (%) . | Toxicities (%) . | |||
---|---|---|---|---|---|---|---|---|---|---|---|
% of patients . | IPI . | Fit . | Unfit/frail . | Fit . | Unfit/frail . | Fit . | Unfit/frail . | ||||
31 | 100 | Italy | ≥70 | 22 | ≥3 | 76 (5-y) | 47 (5-y) | 85 | 76 | 31 | 51 |
32 | 91 | Italy | ≥65 | 30 | ≥3 | 34 (5-y) | 9 (5-y) | 83 | 73 | 28 | 57 |
33 | 88 | Italy | ≥65 | 60 | ≥3 | Median, NR | Median, 8.0 mo | 93 | 52 | — | — |
34 | 173 | Italy | ≥69 | 43 | ≥3 | 84 (2-y) | 47 (2-y) | — | — | — | — |
Reference . | No. of patients . | Location . | Age (y) . | . | . | OS (%) . | ORR (%) . | Toxicities (%) . | |||
---|---|---|---|---|---|---|---|---|---|---|---|
% of patients . | IPI . | Fit . | Unfit/frail . | Fit . | Unfit/frail . | Fit . | Unfit/frail . | ||||
31 | 100 | Italy | ≥70 | 22 | ≥3 | 76 (5-y) | 47 (5-y) | 85 | 76 | 31 | 51 |
32 | 91 | Italy | ≥65 | 30 | ≥3 | 34 (5-y) | 9 (5-y) | 83 | 73 | 28 | 57 |
33 | 88 | Italy | ≥65 | 60 | ≥3 | Median, NR | Median, 8.0 mo | 93 | 52 | — | — |
34 | 173 | Italy | ≥69 | 43 | ≥3 | 84 (2-y) | 47 (2-y) | — | — | — | — |
NR, not reached.