Table 2. Clinical and biological... | American Society of Hematology

Table 2.

Clinical and biological features of the CLL patients from whom the cells for stimulation experiments were isolated

CLL	Rai Binet stage	Age	Sex	IGHV status	CD38	ZAP70	Cytogenetics	Lnf count	Disease	ILT3, MFI
1	2/B	47	M	MUT	Neg	ND	Tris 12	70 900	Progressive	9.7
2	4/C	70	F	U-MUT	Pos	Pos	Neg	39 300	Progressive	14.5
3	4/C	74	M	U-MUT	Pos	Pos	Neg	40 230	Progressive	19.9
4	0/A	85	F	MUT	Neg	Neg	Del 13	42 290	Stable	20.1
5	3/A	58	M	U-MUT	Neg	ND	Del 13	10 990	Stable	27.7
6	1/A	83	F	MUT	Neg	ND	Del 13	74 690	Progressive	4.87
7	2/B	66	M	MUT	ND	ND	Del 13	17 710	Stable	9.71
8	0/A	69	M	U-MUT	Neg	ND	Del 11, del 13	25 320	Progressive	12.4
9	0/A	57	M	MUT	Neg	ND	Del 13	38 020	Stable	12.5
10	0/A	56	F	MUT	Neg	ND	Del 13	20 640	Stable	11.4
11	2/B	84	M	U-MUT	ND	Pos	Neg	24 000	Progressive	9.75
12	2/B	61	M	U-MUT	Pos	ND	Neg	137 000	Progressive	17.2
13	0/A	68	F	MUT	Pos	Neg	Del 13	15 000	Stable	7.5
14	1/B	73	F	ND	Neg	ND	Del 17	20 360	Stable	4.38
15	0/A	77	F	U-MUT	Neg	Neg	Del13, tris 12	10 350	Stable	3
16	0/A	59	F	MUT	ND	ND	ND	26 000	Stable	8.1
17	2/A	77	M	MUT	Neg	Neg	Del 13	7490	Stable	9.2

CLL	Rai Binet stage	Age	Sex	IGHV status	CD38	ZAP70	Cytogenetics	Lnf count	Disease	ILT3, MFI
1	2/B	47	M	MUT	Neg	ND	Tris 12	70 900	Progressive	9.7
2	4/C	70	F	U-MUT	Pos	Pos	Neg	39 300	Progressive	14.5
3	4/C	74	M	U-MUT	Pos	Pos	Neg	40 230	Progressive	19.9
4	0/A	85	F	MUT	Neg	Neg	Del 13	42 290	Stable	20.1
5	3/A	58	M	U-MUT	Neg	ND	Del 13	10 990	Stable	27.7
6	1/A	83	F	MUT	Neg	ND	Del 13	74 690	Progressive	4.87
7	2/B	66	M	MUT	ND	ND	Del 13	17 710	Stable	9.71
8	0/A	69	M	U-MUT	Neg	ND	Del 11, del 13	25 320	Progressive	12.4
9	0/A	57	M	MUT	Neg	ND	Del 13	38 020	Stable	12.5
10	0/A	56	F	MUT	Neg	ND	Del 13	20 640	Stable	11.4
11	2/B	84	M	U-MUT	ND	Pos	Neg	24 000	Progressive	9.75
12	2/B	61	M	U-MUT	Pos	ND	Neg	137 000	Progressive	17.2
13	0/A	68	F	MUT	Pos	Neg	Del 13	15 000	Stable	7.5
14	1/B	73	F	ND	Neg	ND	Del 17	20 360	Stable	4.38
15	0/A	77	F	U-MUT	Neg	Neg	Del13, tris 12	10 350	Stable	3
16	0/A	59	F	MUT	ND	ND	ND	26 000	Stable	8.1
17	2/A	77	M	MUT	Neg	Neg	Del 13	7490	Stable	9.2

All patients analyzed were nontreated, except for patient 2 (detailed in supplemental Methods).

Lnf count, lymphocyte number per mL of blood; MFI, mean fluorescence intensity as determined by flow cytometry; MUT, CLL patients with mutated status of IGHV; ND, not determined; Neg, negative; Pos, positive; U-MUT, CLL patients with unmutated status of IGHV.

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