Treatment-emergent adverse events reported in ≥10% of patients regardless of the cause
| Adverse event (N = 42) . | Grade 1 . | Grade 2 . | Grade 3 . | Grade 4 . | Grade 5 . |
|---|---|---|---|---|---|
| Fatigue | 5 (12) | 14 (33) | 5 (12) | 0 | 0 |
| Diarrhea | 7 (17) | 4 (10) | 4 (10) | 0 | 0 |
| Muscle spasms | 8 (19) | 3 (7) | 1 (2) | 0 | 0 |
| Nausea | 8 (19) | 3 (7) | 0 | 0 | 0 |
| Bruising | 6 (14) | 4 (10) | 0 | 0 | 0 |
| Upper respiratory tract infection | 3 (7) | 5 (12) | 0 | 0 | 0 |
| Pneumonia | 1 (2) | 0 | 4 (10) | 1 (2) | 1 (2) |
| Pyrexia | 4 (10) | 1 (2) | 2 (5) | 0 | 0 |
| Headache | 3 (7) | 2 (5) | 2 (5) | 0 | 0 |
| Fall | 6 (14) | 1 (2) | 0 | 0 | 0 |
| Cough | 4 (10) | 2 (5) | 0 | 0 | 0 |
| Constipation | 3 (7) | 2 (5) | 0 | 0 | 0 |
| Dyspnea | 4 (10) | 0 | 1 (2) | 0 | 0 |
| Hyperglycemia | 1 (2) | 1 (2) | 3 (7) | 0 | 0 |
| Hypokalemia | 0 | 2 (5) | 3 (7) | 0 | 0 |
| Peripheral edema | 1 (2) | 4 (10) | 0 | 0 | 0 |
| Adverse event (N = 42) . | Grade 1 . | Grade 2 . | Grade 3 . | Grade 4 . | Grade 5 . |
|---|---|---|---|---|---|
| Fatigue | 5 (12) | 14 (33) | 5 (12) | 0 | 0 |
| Diarrhea | 7 (17) | 4 (10) | 4 (10) | 0 | 0 |
| Muscle spasms | 8 (19) | 3 (7) | 1 (2) | 0 | 0 |
| Nausea | 8 (19) | 3 (7) | 0 | 0 | 0 |
| Bruising | 6 (14) | 4 (10) | 0 | 0 | 0 |
| Upper respiratory tract infection | 3 (7) | 5 (12) | 0 | 0 | 0 |
| Pneumonia | 1 (2) | 0 | 4 (10) | 1 (2) | 1 (2) |
| Pyrexia | 4 (10) | 1 (2) | 2 (5) | 0 | 0 |
| Headache | 3 (7) | 2 (5) | 2 (5) | 0 | 0 |
| Fall | 6 (14) | 1 (2) | 0 | 0 | 0 |
| Cough | 4 (10) | 2 (5) | 0 | 0 | 0 |
| Constipation | 3 (7) | 2 (5) | 0 | 0 | 0 |
| Dyspnea | 4 (10) | 0 | 1 (2) | 0 | 0 |
| Hyperglycemia | 1 (2) | 1 (2) | 3 (7) | 0 | 0 |
| Hypokalemia | 0 | 2 (5) | 3 (7) | 0 | 0 |
| Peripheral edema | 1 (2) | 4 (10) | 0 | 0 | 0 |
Data are presented as n (%).